Regulation of adiponectin receptor gene expression in diabetic mice
K Inukai, Y Nakashima, M Watanabe… - American Journal …, 2005 - journals.physiology.org
Adiponectin is an adipocyte-derived factor that plays pivotal roles in lipid and glucose
metabolism in muscle and liver. The following two adiponectin receptor types were recently …
metabolism in muscle and liver. The following two adiponectin receptor types were recently …
Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation
N Hosogai, A Fukuhara, K Oshima, Y Miyata… - Diabetes, 2007 - Am Diabetes Assoc
Obesity is linked to a variety of metabolic disorders, such as insulin resistance and
atherosclerosis. Dysregulated production of fat-derived secretory factors, adipocytokines, is …
atherosclerosis. Dysregulated production of fat-derived secretory factors, adipocytokines, is …
Physiological difference between obese (fa/fa) Zucker rats and lean Zucker rats concerning adiponectin
F Oana, H Takeda, K Hayakawa, A Matsuzawa… - Metabolism, 2005 - Elsevier
Obese (fa/fa) Zucker rat is a spontaneous genetic obesity model and, by comparison with
lean Zucker rat, exhibits hyperphagia, hyperinsulinemia, and hyperlipidemia. The aim of this …
lean Zucker rat, exhibits hyperphagia, hyperinsulinemia, and hyperlipidemia. The aim of this …
Adiponectin: a key adipocytokine in metabolic syndrome
Y Okamoto, S Kihara, T Funahashi… - Clinical …, 2006 - portlandpress.com
The metabolic syndrome, a cluster of metabolic disorders often associated with visceral
obesity, increases cardiovascular mortality and morbidity. As the body's largest endocrine …
obesity, increases cardiovascular mortality and morbidity. As the body's largest endocrine …
Adiponectin regulates expression of hepatic genes critical for glucose and lipid metabolism
Q Liu, B Yuan, KA Lo, HC Patterson… - Proceedings of the …, 2012 - National Acad Sciences
The effects of adiponectin on hepatic glucose and lipid metabolism at transcriptional level
are largely unknown. We profiled hepatic gene expression in adiponectin knockout (KO) and …
are largely unknown. We profiled hepatic gene expression in adiponectin knockout (KO) and …
Adipose tissue as an endocrine organ: role of leptin and adiponectin in the pathogenesis of cardiovascular diseases
Obesity, the most common nutritional disorder in industrial countries, is associated with
increased cardiovascular mortality and morbidity. Nevertheless, the molecular basis linking …
increased cardiovascular mortality and morbidity. Nevertheless, the molecular basis linking …
Sustained peripheral expression of transgene adiponectin offsets the development of diet-induced obesity in rats
S Shklyaev, G Aslanidi, M Tennant… - Proceedings of the …, 2003 - National Acad Sciences
Adiponectin (Acrp30) is a physiologically active polypeptide hormone secreted by adipose
tissue that shows insulin-sensitizing, antiinflammatory, and antiatherogenic properties. In …
tissue that shows insulin-sensitizing, antiinflammatory, and antiatherogenic properties. In …
Overexpression of adiponectin targeted to adipose tissue in transgenic mice: impaired adipocyte differentiation
IB Bauche, SA El Mkadem, AM Pottier, M Senou… - …, 2007 - academic.oup.com
Adiponectin (ApN) is an adipokine whose expression and plasma levels are inversely
related to obesity and insulin-resistant states. Chronic repercussions of ApN treatment or …
related to obesity and insulin-resistant states. Chronic repercussions of ApN treatment or …
Macrophage adiponectin expression improves insulin sensitivity and protects against inflammation and atherosclerosis
OBJECTIVE Adiponectin is one of several important metabolically active cytokines secreted
from adipose tissue. Epidemiologic studies have associated low-circulating levels of this …
from adipose tissue. Epidemiologic studies have associated low-circulating levels of this …
[HTML][HTML] Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor γ agonists
AR Nawrocki, MW Rajala, E Tomas, UB Pajvani… - Journal of Biological …, 2006 - ASBMB
The adipose tissue-derived hormone adiponectin improves insulin sensitivity and its
circulating levels are decreased in obesity-induced insulin resistance. Here, we report the …
circulating levels are decreased in obesity-induced insulin resistance. Here, we report the …