Adiponectin is an adipocyte-derived factor that plays pivotal roles in lipid and glucose
metabolism in muscle and liver. The following two adiponectin receptor types were recently …

Obesity is linked to a variety of metabolic disorders, such as insulin resistance and
atherosclerosis. Dysregulated production of fat-derived secretory factors, adipocytokines, is …

Obese (fa/fa) Zucker rat is a spontaneous genetic obesity model and, by comparison with
lean Zucker rat, exhibits hyperphagia, hyperinsulinemia, and hyperlipidemia. The aim of this …

The metabolic syndrome, a cluster of metabolic disorders often associated with visceral
obesity, increases cardiovascular mortality and morbidity. As the body's largest endocrine …

The effects of adiponectin on hepatic glucose and lipid metabolism at transcriptional level
are largely unknown. We profiled hepatic gene expression in adiponectin knockout (KO) and …

Obesity, the most common nutritional disorder in industrial countries, is associated with
increased cardiovascular mortality and morbidity. Nevertheless, the molecular basis linking …

Adiponectin (Acrp30) is a physiologically active polypeptide hormone secreted by adipose
tissue that shows insulin-sensitizing, antiinflammatory, and antiatherogenic properties. In …

Adiponectin (ApN) is an adipokine whose expression and plasma levels are inversely
related to obesity and insulin-resistant states. Chronic repercussions of ApN treatment or …

OBJECTIVE Adiponectin is one of several important metabolically active cytokines secreted
from adipose tissue. Epidemiologic studies have associated low-circulating levels of this …

The adipose tissue-derived hormone adiponectin improves insulin sensitivity and its
circulating levels are decreased in obesity-induced insulin resistance. Here, we report the …