Quercetin up-regulates expressions of peroxisome proliferator-activated receptor γ, liver X receptor α, and ATP binding cassette transporter A1 genes and increases …

SM Lee, J Moon, Y Cho, JH Chung, MJ Shin - Nutrition Research, 2013 - Elsevier
Cholesterol-laden macrophages trigger accumulation of foam cells and increase the risk of
developing atherosclerosis. We hypothesized that quercetin could lower the content of …

[HTML][HTML] Quercetin increases macrophage cholesterol efflux to inhibit foam cell formation through activating PPARγ-ABCA1 pathway

L Sun, E Li, F Wang, T Wang, Z Qin… - International journal of …, 2015 - ncbi.nlm.nih.gov
The accumulation of cholesterol in macrophages could induce the formation of foam cells
and increase the risk of developing atherosclerosis. We wonder if quercetin, one of …

Quercetin regulates hepatic cholesterol metabolism by promoting cholesterol-to-bile acid conversion and cholesterol efflux in rats

M Zhang, Z Xie, W Gao, L Pu, J Wei, C Guo - Nutrition research, 2016 - Elsevier
Quercetin, a common member of the flavonoid family, is widely present in plant kingdom.
Despite that quercetin is implicated in regulating cholesterol metabolism, the molecular …

Molecular mechanism of curcumin on the suppression of cholesterol accumulation in macrophage foam cells and atherosclerosis

JF Zhao, LC Ching, YC Huang, CY Chen… - Molecular nutrition & …, 2012 - Wiley Online Library
Scope Curcumin, a potent antioxidant extracted from Curcuma longa, confers protection
against atherosclerosis, yet the detailed mechanisms are not fully understood. In this study …

Quercetin improves macrophage reverse cholesterol transport in apolipoprotein E-deficient mice fed a high-fat diet

Y Cui, P Hou, F Li, Q Liu, S Qin, G Zhou, X Xu… - Lipids in health and …, 2017 - Springer
Background Quercetin, one of the most widely distributed flavonoids in plants, has been
demonstrated to reduce hyperlipidaemia and atherosclerotic lesion formation. Reverse …

Quercetin induces the selective uptake of HDL-cholesterol via promoting SR-BI expression and the activation of the PPARγ/LXRα pathway

K Ren, T Jiang, GJ Zhao - Food & function, 2018 - pubs.rsc.org
Reverse cholesterol transport (RCT) is the process to deliver cholesterol to the liver for
further excretion and involves scavenger receptor class B type I (SR-BI)-mediated selective …

Purple perilla extracts with α-asarone enhance cholesterol efflux from oxidized LDL-exposed macrophages

SH Park, JH Paek, D Shin, JY Lee… - International …, 2015 - spandidos-publications.com
The cellular accumulation of cholesterol is critical in the development and progression of
atherosclerosis. ATP-binding cassette (ABC) transporters play an essential role in mediating …

Quercetin-3-O-glucuronide induces ABCA1 expression by LXRα activation in murine macrophages

K Ohara, H Wakabayashi, Y Taniguchi, K Shindo… - Biochemical and …, 2013 - Elsevier
Reverse cholesterol transport (RCT) removes excess cholesterol from macrophages to
prevent atherosclerosis. ATP-binding cassette, subfamily A, member 1 (ABCA1) is a crucial …

Quercetin enhances ABCA1 expression and cholesterol efflux through a p38-dependent pathway in macrophages

YC Chang, TS Lee, AN Chiang - Journal of lipid research, 2012 - ASBMB
ATP-binding cassette transporter A1 (ABCA1) plays a crucial role in exporting cholesterol
from macrophages, a function relevant to its involvement in the prevention of …

[PDF][PDF] Quercetin upregulates ABCA1 expression through liver X receptor alpha signaling pathway in THP-1 macrophages.

Y Lu, YP Jia - European Review for Medical & Pharmacological …, 2016 - europeanreview.org
OBJECTIVES: Quercetin has been reported to have the activities of antioxidant, anti-
inflammatory, anti-virus, anti-cancer and so on. Many studies showed that quercetin could …