Vaccines for HIV, malaria and TB remain high priorities, especially for sub-Saharan
populations. The question is: will vaccines currently in development for these diseases …

In areas co-endemic for helminth parasites and HIV/AIDS, infants are often administered
vaccines prior to infection with immune modulatory helminth parasites. Systemic Th2 biasing …

A number of HIV-1 vaccines are in various phases of clinical trials and many more are in the
developmental pipeline. Vaccines are especially needed for developing countries where …

The AIDS epidemic in the developing world represents a major global crisis and an effective
vaccine is imperative. However, many parasites are common in developing countries and …

Background We have evaluated an attenuated Listeria monocytogenes (Lm) candidate
vaccine vector in nonhuman primates using a delivery regimen relying solely on oral …

HIV-1 prevalence is highest in developing countries; similarly helminth parasites are often
highly endemic in these same areas. Helminths are strong immune modulators, and …

Listeria monocytogenes is an attractive biologic vaccine vector against HIV because it
induces a strong cell mediated immune response, can be delivered by mucosal routes, can …

Future HIV vaccines are expected to induce effective Th1 cell-mediated and Env-specific
antibody responses that are necessary to offer protective immunity to HIV infection …

To date, there are no proven vaccines against any form of leishmaniasis. The development
of live attenuated vectors shows promise in the field of Leishmania vaccination because …

ABSTRACT CD8+ T cells are a major component of the adaptive response of a host to
infections by viruses and other intracellular pathogenic agents. However, because of the …