To explore sex differences in reinstatement of conditioned place preference, we subjected
intact male and female Long Evans rats to an extended conditioned place preference (CPP) …

Although the protective effects of social bonds on drug use/abuse have been well
documented, we know little about the underlying neural mechanisms. Using the prairie vole …

In this study, we measured conditioned place preference (CPP) responses to cocaine
following subchronic administration of the recreationally abused drug (±)‐3, 4 …

The rewarding effect of cocaine as reflected by the development of conditioned place
preference was examined in C57BL/6J and 129/J mice. Cocaine was administered in a …

Cocaine conditioned place preference (CPP) is more persistent in food-restricted than ad
libitum fed rats. This study assessed whether food restriction acts during conditioning and/or …

Reinstatement of drug-seeking behavior in animals is relevant to drug relapse in humans. In
the present study, we employed the conditioned place preference (CPP) paradigm to …

Conditioned place preference and locomotor sensitization are rodent behavioral models
commonly used to investigate the actions of drugs of abuse. However, few studies have …

Outbred, male Sprague–Dawley rats can be classified as either low or high cocaine
responders (LCRs or HCRs, respectively) based on cocaine-induced locomotor activity in an …

Chronic physical activity (exercise) may be beneficial in the prevention of substance use
disorders; however, the extent to which physical activity can interfere with the reinforcing …

The conditioned place preference paradigm is a standard preclinical behavioral model used
to study the rewarding and aversive effects of drugs. Although a number of different designs …