Addiction and substance abuse are found ubiquitously throughout human society. In the
United States, these disorders are responsible for amassing hundreds of billions of dollars in …

The conditioned place preference paradigm is a standard preclinical behavioral model used
to study the rewarding and aversive effects of drugs. Although a number of different designs …

The interaction between social factors and alcohol addiction is complex, with potential for
both positive and negative contributions to drug use and abstinence. Positive social …

Conditioned place preference (CPP) continues to be one of the most popular models to
study the motivational effects of drugs and non‐drug treatments in experimental animals …

While social context has long been considered central to substance use disorder prevention
and treatment and many drug-taking events occur in social settings, experimental research …

The conditioned place preference (CPP) model has been widely used to evaluate the
rewarding effects of abused drugs, and recently, the extinction and reinstatement phases of …

Cocaine-treated rats acquired a preference for cocaine-associated contextual stimuli (CS)
relative to saline-injected control rats. However, when animals were given repeated tests for …

To explore the way in which drugs act to reinstate drug-seeking behavior, we studied drug-
induced reinstatement of a cocaine-induced conditioned place preference (CPP). In a series …

Place conditioning is a classical conditioning paradigm in which animals (typically rats or
mice) learn to associate the effects of a drug (or other discrete treatment) with a particular …

Female rats exhibit greater intake and motivation to self-administer cocaine. In females but
not males, isolation by itself is a stressor, which could lead to increased drug intake …