Grape extract protects mitochondria from oxidative damage and improves locomotor dysfunction and extends lifespan in a Drosophila Parkinson's disease model
A botanical extract (Regrapex-R®) prepared from whole grape (Vitis vinifera) and
Polygonum cuspidatum, which contains polyphenols, including flavans, anthocyanins …
Polygonum cuspidatum, which contains polyphenols, including flavans, anthocyanins …
Grape skin extract improves muscle function and extends lifespan of a Drosophila model of Parkinson's disease through activation of mitophagy
Recent studies suggest that moderate red wine consumption may confer several health
benefits, including protection against heart disease, certain cancers and multiple age …
benefits, including protection against heart disease, certain cancers and multiple age …
Resveratrol exerts its neuroprotective effect by modulating mitochondrial dysfunctions and associated cell death during cerebral ischemia
Free radicals are known to cause secondary neuronal damage in cerebral
ischemia/reperfusion (I/R). We investigated here the neuroprotective effect of resveratrol, a …
ischemia/reperfusion (I/R). We investigated here the neuroprotective effect of resveratrol, a …
Resveratrol and/or exercise training counteract aging-associated decline of physical endurance in aged mice; targeting mitochondrial biogenesis and function
MH Muhammad, MM Allam - The Journal of Physiological Sciences, 2018 - Springer
Mitochondrial dysfunction and decreased mitochondrial content are hallmarks of aging that
leads to decreased physical endurance. Our aim was to explore the anti-aging effect of …
leads to decreased physical endurance. Our aim was to explore the anti-aging effect of …
Resveratrol-induced limitation of dysfunction of mitochondria isolated from rat brain in an anoxia-reoxygenation model
R Zini, C Morin, A Bertelli, AAE Bertelli, JP Tillement - Life sciences, 2002 - Elsevier
Resveratrol protection on the main functions of purified rat brain mitochondria submitted to
anoxia-reoxygenation was investigated. Resveratrol (< 0.1 μM) reversed partly (23.3%) the …
anoxia-reoxygenation was investigated. Resveratrol (< 0.1 μM) reversed partly (23.3%) the …
Resveratrol and brain mitochondria: a review
FR Jardim, FT de Rossi, MX Nascimento… - Molecular …, 2018 - Springer
Abstract Resveratrol (3, 4', 5-trihydroxystilbene; C 14 H 12 O 3) is a polyphenolic phytoalexin
found in grapes, berries, peanuts, and wines. Resveratrol has been viewed as an …
found in grapes, berries, peanuts, and wines. Resveratrol has been viewed as an …
Resveratrol affects differently rat liver and brain mitochondrial bioenergetics and oxidative stress in vitro: investigation of the role of gender
AC Moreira, AM Silva, MS Santos, VA Sardão - Food and chemical …, 2013 - Elsevier
Resveratrol (3, 5, 4′-trihydroxy-trans stilbene) is commonly recognized by its antioxidant
properties. Despite its beneficial qualities, the toxic effects of this natural compound are still …
properties. Despite its beneficial qualities, the toxic effects of this natural compound are still …
Grape seed proanthocyanidin lowers brain oxidative stress in adult and middle-aged rats
SA Devi, BKS Chandrasekar, KR Manjula… - Experimental …, 2011 - Elsevier
There is growing concern over the increasing instances of decline in cognitive abilities with
aging in humans. The present study evaluated the benefits of the natural antioxidant, grape …
aging in humans. The present study evaluated the benefits of the natural antioxidant, grape …
[HTML][HTML] Signaling mechanisms underlying the glioprotective effects of resveratrol against mitochondrial dysfunction
Resveratrol, a polyphenol found in grapes and red wine, exhibits antioxidant, anti-
inflammatory, anti-aging and, neuroprotective effects. Resveratrol also plays a significant …
inflammatory, anti-aging and, neuroprotective effects. Resveratrol also plays a significant …
Protective Effects of Salidroside in the MPTP/MPP+-Induced Model of Parkinson's Disease through ROS–NO-Related Mitochondrion Pathway
S Wang, H He, L Chen, W Zhang, X Zhang… - Molecular neurobiology, 2015 - Springer
Parkinson's disease is a progressive neurodegenerative disease causing tremor, rigidity,
bradykinesia, and gait impairment. Oxidative stress and mitochondrial dysfunction play …
bradykinesia, and gait impairment. Oxidative stress and mitochondrial dysfunction play …