Our purpose was to determine if cytokines are produced systemically during acute
pancreatitis. Proinflammatory cytokines are elevated during acute pancreatitis and have …

Background: The systemic manifestations of acute pancreatitis are responsible for the
majority of pancreatitis-associated morbidity and mortality and are now believed to be due to …

The importance of interleukin-1β (IL-1β) in the pathogenesis of acute pancreatitis has been
demonstrated by dramatic attenuation of pancreatic destruction and significant increases in …

Objectives We aimed at synchronously examining the early time course of 4 proinflammatory
cytokines as predictive factors for development of organ failure in patients with acute …

Inflammatory mediators play a key role in acute pancreatitis and the resultant multiple organ
dysfunction syndrome, which is the primary cause of death in this condition. Recent studies …

BACKGROUND The time course and relationship between circulating and local cytokine
concentrations, pancreatic inflammation, and organ dysfunction in acute pancreatitis are …

Severe, acute pancreatitis is commonly associated with a systemic illness which may result
in multiple organ failure. There is evidence that an aberrant immune response, involving …

The relationship between inflammation and proteolytic activation in pancreatitis is an
unresolved issue in pancreatology. The purpose of this study was to define the influence of …

Objective. Acute pancreatitis (AP) is an inflammatory disorder that develops a complex
cascade of immunological events. The local and systemic immune status and inflammatory …

Acute pancreatitis (AP) is a disease characterized by abdominal pain and elevations in the
serum levels of amylase and lipase. 27 A key feature of AP is the elaboration of an …