Whole exome sequencing identifies putative predictors of recurrent prostate cancer with high accuracy

J Liu, R Mao, G Ren, X Liu, Y Zhang… - OMICS: A Journal of …, 2019 - liebertpub.com
Prostate cancer (PCa) is a highly common cancer among men but lacks robust diagnostics
that can predict disease recurrence after initial treatment, for example, with radical …

Exome sequencing of prostate cancer supports the hypothesis of independent tumour origins

J Lindberg, D Klevebring, W Liu, M Neiman, J Xu… - European urology, 2013 - Elsevier
BACKGROUND: Prostate cancer (PCa) is a clinically and pathologically heterogeneous
disease. The rapid development of sequencing technology has the potential to deliver new …

Identification of a transcriptomic prognostic signature by machine learning using a combination of small cohorts of prostate cancer

B Vittrant, M Leclercq, ML Martin-Magniette… - Frontiers in …, 2020 - frontiersin.org
Determining which treatment to provide to men with prostate cancer (PCa) is a major
challenge for clinicians. Currently, the clinical risk-stratification for PCa is based on clinico …

Gene expression changes and associated pathways involved in the progression of prostate cancer advanced stages

EA Pudova, GS Krasnov, AA Kobelyatskaya… - Frontiers in …, 2021 - frontiersin.org
Prostate cancer (PC) is one of the most common cancers among men worldwide, and
advanced PCs, such as locally advanced PC (LAPC) and castration-resistant PC (CRPC) …

[HTML][HTML] Five-gene signature associating with Gleason score serve as novel biomarkers for identifying early recurring events and contributing to early diagnosis for …

L Zhang, Y Li, X Wang, Y Ping, D Wang, Y Cao… - Journal of …, 2021 - ncbi.nlm.nih.gov
Background: Compared to non-recurrent type, recurrent prostate adenocarcinoma (PCa) is
highly fatal, and significantly shortens the survival time of affected patients. Early and …

Principal component analysis of RNA-seq data unveils a novel prostate cancer-associated gene expression signature

Y Perera, A Gonzalez, R Perez - bioRxiv, 2020 - biorxiv.org
Prostate cancer is a highly heterogeneous disease and the second more common tumor in
males. Molecular and genetic profiles are currently used to identify subtypes and to guide …

Molecular evolution of early-onset prostate cancer identifies molecular risk markers and clinical trajectories

C Gerhauser, F Favero, T Risch, R Simon, L Feuerbach… - Cancer cell, 2018 - cell.com
Identifying the earliest somatic changes in prostate cancer can give important insights into
tumor evolution and aids in stratifying high-from low-risk disease. We integrated whole …

[HTML][HTML] Advances in genetics: widening our understanding of prostate cancer

AC Pine, FF Fioretti, GN Brooke, CL Bevan - F1000Research, 2016 - ncbi.nlm.nih.gov
Prostate cancer is a leading cause of cancer-related death in Western men. Our
understanding of the genetic alterations associated with disease predisposition …

[HTML][HTML] A four gene signature predictive of recurrent prostate cancer

J Komisarof, M McCall, L Newman, W Bshara… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Prostate cancer is the most common form of non-dermatological cancer among US men,
with an increasing incidence due to the aging population. Patients diagnosed with clinically …

PCaDB-a comprehensive and interactive database for transcriptomes from prostate cancer population cohorts

R Li, J Zhu, WD Zhong, Z Jia - BioRxiv, 2021 - biorxiv.org
Prostate cancer (PCa) is a heterogeneous disease with highly variable clinical outcomes
which presents enormous challenges in the clinical management. A vast amount of …