Leucine aminopeptidase (LAP) is a vital proteolytic enzyme, and its overexpression is often
associated with many physiological diseases, such as liver dysfunction and breast cancer …

The fluorescence emission behavior of bioactive dietary polyphenols in serum albumin has
been explored in order to understand their spectroscopic properties along with their binding …

Clinical drug-induced organ toxicity and damage have been recognized as an important
public health issue, and an effective approach capable of in vivo detection of biomarkers …

T he accurate detection of related biomarkers at early stage is crucial in diagnosis and
therapy of cancer. Small molecule fluorescence probes stand out acting as efficient tools to …

Aggregation-induced emission (AIE) provides a new strategy for preparing fluorescent
sensors in aggregated state. In this paper, a series of crown ether-bridged bis …

Abnormal level of alkaline phosphatase (ALP) activity has been linked to many diseases in
human. The development of fluorescent molecular probes that can report the expression …

Optical imaging including fluorescence and luminescence is the most popular method for
the in vivo imaging in mice. Luminescence imaging is considered to be superior to …

We synthesized a new organic fluorescent dye named resveratrone glucoside from the
photoreaction of naturally-occurring phytoalexin compound resveratrol glucoside …

Diabetic nephropathy (DN) is one of the most serious and general complications of diabetes,
while schedules for prevention and treatment are unsatisfactory. Leucine aminopeptidase …

Bioluminescence (BL), the emission light resulting from the enzyme-catalyzed oxidative
reaction, is a powerful imaging modality for monitoring biological phenomena both in vitro …