Development of organ dysfunction discriminates sepsis from uncomplicated infection. The
paradigm shift implicated by the new sepsis-3 definition holds that initial impairment of any …

Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host
response to infection. This definition, updated in 2016, shifted the conceptual focus from …

Sepsis and septic shock lead to considerable morbidity and mortality in developed and
developing countries. Despite advances in understanding the innate immune events that …

Sepsis is described as a life-threatening organ dysfunction and a heterogeneous syndrome
that is a leading cause of morbidity and mortality in intensive care settings. Severe sepsis …

Sepsis is defined as “a life‐threatening organ dysfunction caused by dysregulated host
systemic inflammatory and immune response to infection.” At present, sepsis continues to …

Sepsis is defined as life-threatening organ dysfunction caused by dysregulated host
systemic inflammatory and immune response to infection. Over decades, advanced …

Sepsis is one of the most common reasons for critically ill patients to be admitted to an
intensive care unit and, despite advances in overall medical care, it represents a major …

Review on sepsis mediators, and roles in innate and adaptive immune systems, as well as
implications for therapeutics. Sepsis refers to severe systemic inflammation in response to …

Molecular Pathways in Sepsis Pathogenesis: Recent Advances and Therapeutic Avenues
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Sepsis is defined as a life-threatening organ dysfunction that is caused by a dysregulated
host response to infection. In sepsis, the immune response that is initiated by an invading …