Ursolic acid, a pentacyclic triterpene compound with low toxicity and easy availability, has a
variety of biological activities, including antitumor, antioxidant, antihepatitis, anti …

Ursolic acid (UA) as a multiple bioactive native compound has recently been demonstrated
to treat sepsis in animal models. However, the beneficial effects of UA in sepsis‑induced …

Inflammation plays a pivotal role in the pathogenesis of diabetic nephropathy (DN).
Overexpression of inflammatory chemokine and cytokines is involved in the development of …

Ursolic acid (UA) is a triterpenoid isolated from Chinese herbal medicine. It is extensively
distributed in the plant kingdom in at least 63 Chinese herbal medicines of 26 families. UA …

In the present study, the protective effect and the potential underlying mechanism of
rutaecarpine (Ru) on renal ischemia reperfusion injury (IRI) in rats were investigated. A renal …

Abstract Ischemic/reperfusion (I/R) injury is the primary cause of acute kidney injury (AKI).
Hydroxysafflor yellow A (HSYA), a natural compound isolated from Carthamus tinctorius L …

Inflammation and apoptosis are the major contributors to the mechanisms of acute kidney
injury (AKI) due to renal ischemia-reperfusion injury (IRI). Maslinic acid (MA), a pentacyclic …

Ursolic acid (UA), a common pentacyclic triterpenoid compound, has been reported to have
many benefits and medicinal properties. However, its protective effects against carbon …

Abstract Ischemia‑reperfusion (I/R) often leads to acute kidney injury, chronic renal failure
and kidney transplantation failure. Glycyrrhizin is extracted from Glycyrrhiza glabra roots and …

Objective To investigate the effect of ursolic acid (UA) on the alloxan-induced kidney injury
in diabetic mice and explored its possible mechanisms. Methods Diabetes mellitus was …