A 4‐microRNA signature for survival prognosis in pediatric and adolescent acute myeloid leukemia

R Zhu, W Lin, W Zhao, F Fan, L Tang… - Journal of cellular …, 2019 - Wiley Online Library
Acute myeloid leukemia (AML) is a hematologic malignancy with significant molecular
heterogeneity. MicroRNAs (miRNAs) play a critical role in AML diagnosis, pathogenesis …

[HTML][HTML] A 3-miRNA signature predicts prognosis of pediatric and adolescent cytogenetically normal acute myeloid leukemia

R Zhu, W Zhao, F Fan, L Tang, J Liu, T Luo, J Deng… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Acute myeloid leukemia is a hematologic malignancy with significant molecular
heterogeneity. MicroRNAs have important biological functions and play critical roles in …

MiRNA expression as outcome predictor in pediatric AML: systematic evaluation of a new model

I Ellson, J Martorell-Marugán, P Carmona-Sáez… - NPJ Genomic …, 2024 - nature.com
Accurately predicting patient outcomes is essential for optimizing treatment and improving
outcomes in pediatric acute myeloid leukemia (AML). In recent years, microRNAs have …

[HTML][HTML] Classification of pediatric acute myeloid leukemia based on miRNA expression profiles

A Obulkasim, JE Katsman-Kuipers, L Verboon… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Pediatric acute myeloid leukemia (AML) is a heterogeneous disease with respect to biology
as well as outcome. In this study, we investigated whether known biological subgroups of …

A 3-microRNA scoring system for prognostication in de novo acute myeloid leukemia patients

MK Chuang, YC Chiu, WC Chou, HA Hou, EY Chuang… - Leukemia, 2015 - nature.com
As a highly heterogeneous disease, acute myeloid leukemia (AML) needs fine risk
stratification to get an optimal outcome of patients. MicroRNAs have florid biological …

Screening of prognostic risk microRNAs for acute myeloid leukemia

HY Gao, W Wang, XG Luo, YF Jiang, X He, P Xu… - …, 2018 - Taylor & Francis
Objectives This study aimed to investigate the risk miRNAs (microRNAs) for AML (acute
myeloid leukemia) prognosis and related regulatory mechanisms. Methods MiRNA and …

MicroRNA expression-based model indicates event-free survival in pediatric acute myeloid leukemia

EL Lim, DL Trinh, RE Ries, J Wang… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Children with acute myeloid leukemia (AML) whose disease is refractory to
standard induction chemotherapy therapy or who experience relapse after initial response …

[HTML][HTML] MicroRNA biomarker identification for pediatric acute myeloid leukemia based on a novel bioinformatics model

W Yan, L Xu, Z Sun, Y Lin, W Zhang, J Chen, S Hu… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Acute myeloid leukemia (AML) in children is a complex and heterogeneous disease. The
identification of reliable and stable molecular biomarkers for diagnosis, especially early …

MicroRNA patterns associated with clinical prognostic parameters and CNS relapse prediction in pediatric acute leukemia

H Zhang, XQ Luo, P Zhang, LB Huang, YS Zheng… - PloS one, 2009 - journals.plos.org
Background Recent reports have indicated that microRNAs (miRNAs) play a critical role in
malignancies, and regulations in the progress of adult leukemia. The role of miRNAs in …

MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia

S Mi, J Lu, M Sun, Z Li, H Zhang… - Proceedings of the …, 2007 - National Acad Sciences
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, whereas acute
myeloid leukemia (AML) is the most common acute leukemia in adults. In general, ALL has a …