[HTML][HTML] Trehalose is a versatile and long-lived chaperone for desiccation tolerance
H Tapia, DE Koshland - Current Biology, 2014 - cell.com
Background Diverse organisms across taxa are desiccation tolerant, capable of surviving
extreme water loss. Remarkably, desiccation tolerant organisms can survive years without …
extreme water loss. Remarkably, desiccation tolerant organisms can survive years without …
Increasing intracellular trehalose is sufficient to confer desiccation tolerance to Saccharomyces cerevisiae
Diverse organisms capable of surviving desiccation, termed anhydrobiotes, include species
from bacteria, yeast, plants, and invertebrates. However, most organisms are sensitive to …
from bacteria, yeast, plants, and invertebrates. However, most organisms are sensitive to …
[HTML][HTML] Intracellular trehalose improves osmotolerance but not desiccation tolerance in mammalian cells
AG de Castro, A Tunnacliffe - FEBS letters, 2000 - Elsevier
Trehalose has been shown to play a role in osmotolerance or desiccation tolerance in some
microorganisms, anhydrobiotic invertebrates and resurrection plants. To test whether …
microorganisms, anhydrobiotic invertebrates and resurrection plants. To test whether …
[HTML][HTML] Trehalose and tardigrade CAHS proteins work synergistically to promote desiccation tolerance
Tardigrades are microscopic animals renowned for their ability to survive extreme
desiccation. Unlike many desiccation-tolerant organisms that accumulate high levels of the …
desiccation. Unlike many desiccation-tolerant organisms that accumulate high levels of the …
[HTML][HTML] New insight into the mechanisms protecting bacteria during desiccation
E Laskowska, D Kuczyńska-Wiśnik - Current genetics, 2020 - Springer
Desiccation is a common stress that bacteria face in the natural environment, and thus, they
have developed a variety of protective mechanisms to mitigate the damage caused by water …
have developed a variety of protective mechanisms to mitigate the damage caused by water …
Genetic Analysis of Desiccation Tolerance in Saccharomyces cerevisiae
Desiccation tolerance, the ability to survive nearly total dehydration, is a rare strategy for
survival and reproduction observed in all taxa. However, the mechanism and regulation of …
survival and reproduction observed in all taxa. However, the mechanism and regulation of …
Anhydrobiotic engineering of bacterial and mammalian cells: is intracellular trehalose sufficient?
A Tunnacliffe, AG de Castro, M Manzanera - Cryobiology, 2001 - Elsevier
Anhydrobiotic engineering aims to confer a high degree of desiccation tolerance on
otherwise sensitive living organisms and cells by adopting the strategies of anhydrobiosis …
otherwise sensitive living organisms and cells by adopting the strategies of anhydrobiosis …
Trehalose is required for conformational repair of heat‐denatured proteins in the yeast endoplasmic reticulum but not for maintenance of membrane traffic functions …
M Simola, AL Hänninen, SM Stranius… - Molecular …, 2000 - Wiley Online Library
Saccharomyces cerevisiae cells grown at physiological temperature 24° C require
preconditioning at 37° C to acquire tolerance towards brief exposure to 48–50° C. During …
preconditioning at 37° C to acquire tolerance towards brief exposure to 48–50° C. During …
Intracellular trehalose is neither necessary nor sufficient for desiccation tolerance in yeast
S Ratnakumar, A Tunnacliffe - FEMS yeast research, 2006 - academic.oup.com
Trehalose is thought to be important for desiccation tolerance in a number of organisms,
including Saccharomyces cerevisiae, but there is limited in vivo evidence to support this …
including Saccharomyces cerevisiae, but there is limited in vivo evidence to support this …
[HTML][HTML] Multiple effects of trehalose on protein folding in vitro and in vivo
MA Singer, S Lindquist - Molecular cell, 1998 - cell.com
The disaccharide trehalose is produced in large quantities by diverse organisms during a
variety of stresses. Trehalose prevents proteins from denaturing at high temperatures in …
variety of stresses. Trehalose prevents proteins from denaturing at high temperatures in …