Mutations in the progranulin (PGRN) gene on chromosome 17 have been shown to be
responsible for one non‐tauopathy subtype of familial frontotemporal lobar degeneration …

Frontotemporal lobar degeneration with ubiquitinated inclusions (FTLD-U) is the most
common neuropathology associated with the clinical syndrome of frontotemporal dementia …

Frontotemporal lobar degeneration (FTLD) can be pathologically subdivided into tau-
positive and tau-negative types. The most common tau-negative variant is FTLD with …

The most common pathology in frontotemporal dementia (FTD) is tau-negative, ubiquitin-
immunoreactive (ub-ir) neuronal inclusions (FTLD-U). Recently, we identified mutations in …

Frontotemporal lobar degeneration (FTLD) refers to a focal, non-Alzheimer form of cerebral
degeneration that encompasses the distinct clinical syndromes of frontotemporal dementia …

The most common histologic feature in patients with frontotemporal lobar degeneration
(FTLD) is intracellular brain inclusions of yet uncharacterized proteins that react with …

Frontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-U) is a common
neuropathological subtype of frontotemporal dementia. Although this subtype of …

Mutations in the progranulin gene (PGRN), on chromosome 17q21, have recently been
identified as a major cause of familial frontotemporal dementia (FTD). These cases have a …

The past year has seen a number of significant advances in our understanding of the
neuropathological and molecular genetic basis of frontotemporal lobar degeneration …

Genetic, clinical, and neuropathologic heterogeneity have been observed in frontotemporal
lobar degeneration with ubiquitin (Ubq)-positive inclusions (FTLD-U) and FTLD-U with motor …