Mineralization initiation of MC3T3‐E1 preosteoblast is suppressed under simulated microgravity condition

L Hu, J Li, A Qian, F Wang, P Shang - Cell Biology International, 2015 - Wiley Online Library
Microgravity decreases the differentiation of osteoblast. However, as this process is
multistage and complex, the mechanism by which microgravity inhibits osteoblast …

[HTML][HTML] Histological analysis of the effects of a static magnetic field on bone healing process in rat femurs

E Puricelli, LM Ulbrich, D Ponzoni, JJC Filho - Head & Face Medicine, 2006 - Springer
Background The aim of this study was to investigate, in vivo, the quality of bone healing
under the effect of a static magnetic field, arranged inside the body. Methods A metallic …

Large gradient high magnetic field affects the association of MACF1 with actin and microtubule cytoskeleton

AR Qian, LF Hu, X Gao, W Zhang, SM Di… - … : Journal of the …, 2009 - Wiley Online Library
The intense inhomogeneous magnetic fields acting on the diamagnetic materials naturally
present in cells can generate strong magnetic forces. We have developed a …

[HTML][HTML] Effects of constant magnetic field to the proliferation rate of human fibroblasts grown onto different substrates: Tissue culture polystyrene, polyacrylamide …

FA Blyakhman, GY Melnikov, EB Makarova… - Nanomaterials, 2020 - mdpi.com
The static magnetic field was shown to affect the proliferation, adhesion and differentiation of
various types of cells, making it a helpful tool for regenerative medicine, though the …

Early responses of osteoblast-like cells to different mechanical signals through various signaling pathways

J Liu, T Liu, Y Zheng, Z Zhao, Y Liu, H Cheng… - Biochemical and …, 2006 - Elsevier
This study was to examine the effects of mechanical stimuli alone and coupled with some
inhibitors of related signaling pathways on early cellular responses. MG-63 cells were …

16 T high static magnetic field inhibits receptor activator of nuclear factor kappa‐Β ligand‐induced osteoclast differentiation by regulating iron metabolism in Raw264 …

D Dong, J Yang, G Zhang, T Huyan… - Journal of Tissue …, 2019 - Wiley Online Library
High static magnetic fields (HiSMFs) are usually defined as those SMFs with intensities≥ 1
T. Although many studies have indicated that SMFs have positive effects on bone tissue …

Cell differentiation and p38MARK cascade are inhibited in human osteoblasts cultured in a three-dimensional clinostat

L Yuge, I Hide, T Kumagai, Y Kumei, S Takeda… - In Vitro Cellular & …, 2003 - Springer
Summary A three-dimensional (3D) clinostat is a device for multidirectional G force
generation. By controlled rotation of two axes, a 3D clinostat cancels the cumulative gravity …

[HTML][HTML] Physical stimulations and their osteogenesis-inducing mechanisms

C Shuai, W Yang, S Peng, C Gao, W Guo… - … Journal of Bioprinting, 2018 - ncbi.nlm.nih.gov
Physical stimulations such as magnetic, electric and mechanical stimulation could enhance
cell activity and promote bone formation in bone repair process via activating signal …

Magnetic field stress induces expression of hsp70

R Goodman, M Blank - Cell Stress & Chaperones, 1998 - ncbi.nlm.nih.gov
Magnetic fields with frequencies lower than 300 Hz and field strengths less than 1 Gauss
(1000 mG) induce a variety of effects in cells and tissues (for reviews see Blank 1995; …

Modeled microgravity stimulates osteoclastogenesis and bone resorption by increasing osteoblast RANKL/OPG ratio

N Rucci, A Rufo, M Alamanou… - Journal of cellular …, 2007 - Wiley Online Library
Mechanical unloading causes detrimental effects on the skeleton, but the underlying
mechanisms are still unclear. We investigated the effect of microgravity on osteoblast ability …