In vivo functional genomics of Pseudomonas aeruginosa for high‐throughput screening of new virulence factors and antibacterial targets
E Potvin, DE Lehoux, I Kukavica‐Ibrulj… - Environmental …, 2003 - Wiley Online Library
Pseudomonas aeruginosa is a model for studying opportunistic pathogens that are highly
resistant to most classes of antibiotics and cause chronic pulmonary infections. We have …
resistant to most classes of antibiotics and cause chronic pulmonary infections. We have …
Intrinsic and Environmental Mutagenesis Drive Diversification and Persistence of Pseudomonas aeruginosa in Chronic Lung Infections
A Rodríguez-Rojas, A Oliver… - Journal of Infectious …, 2012 - academic.oup.com
Pseudomonas aeruginosa is a versatile opportunistic pathogen causing a wide variety of
hospital-acquired acute infections in immunocompromised patients as well as chronic …
hospital-acquired acute infections in immunocompromised patients as well as chronic …
Pseudomonas aeruginosa : new insights into pathogenesis and host defenses
SL Gellatly, REW Hancock - Pathogens and disease, 2013 - academic.oup.com
Pseudomonas aeruginosa is a metabolically versatile bacterium that can cause a wide
range of severe opportunistic infections in patients with serious underlying medical …
range of severe opportunistic infections in patients with serious underlying medical …
Extensive Genomic Plasticity in Pseudomonas aeruginosa Revealed by Identification and Distribution Studies of Novel Genes among Clinical Isolates
K Shen, S Sayeed, P Antalis, J Gladitz… - Infection and …, 2006 - Am Soc Microbiol
The distributed genome hypothesis (DGH) states that each strain within a bacterial species
receives a unique distribution of genes from a population-based supragenome that is many …
receives a unique distribution of genes from a population-based supragenome that is many …
[HTML][HTML] Positive Signature-Tagged Mutagenesis in Pseudomonas aeruginosa: Tracking Patho-Adaptive Mutations Promoting Airways Chronic Infection
I Bianconi, A Milani, C Cigana, M Paroni… - PLoS …, 2011 - journals.plos.org
The opportunistic pathogen Pseudomonas aeruginosa can establish life-long chronic
infections in the airways of cystic fibrosis (CF) patients. Persistent lifestyle is established with …
infections in the airways of cystic fibrosis (CF) patients. Persistent lifestyle is established with …
[HTML][HTML] Reconstruction of the metabolic network of Pseudomonas aeruginosa to interrogate virulence factor synthesis
Virulence-linked pathways in opportunistic pathogens are putative therapeutic targets that
may be associated with less potential for resistance than targets in growth-essential …
may be associated with less potential for resistance than targets in growth-essential …
Integrated whole‐genome screening for Pseudomonas aeruginosa virulence genes using multiple disease models reveals that pathogenicity is host specific
P seudomonas aeruginosa is a multi‐host opportunistic pathogen causing a wide range of
diseases because of the armoury of virulence factors it produces, and it is difficult to …
diseases because of the armoury of virulence factors it produces, and it is difficult to …
Targeting mechanisms of Pseudomonas aeruginosa pathogenesis
E Kipnis, T Sawa, J Wiener-Kronish - Medecine et maladies infectieuses, 2006 - Elsevier
Pseudomonas aeruginosa is an opportunistic pathogen responsible for ventilator-acquired
pneumonia, acute lower respiratory tract infections in immunocompromised patients and …
pneumonia, acute lower respiratory tract infections in immunocompromised patients and …
[HTML][HTML] What It Takes to Be a Pseudomonas aeruginosa? The Core Genome of the Opportunistic Pathogen Updated
Pseudomonas aeruginosa is an opportunistic bacterial pathogen able to thrive in highly
diverse ecological niches and to infect compromised patients. Its genome exhibits a mosaic …
diverse ecological niches and to infect compromised patients. Its genome exhibits a mosaic …
Elucidating the molecular mechanisms of bacterial virulence using non‐mammalian hosts
S Mahajan‐Miklos, LG Rahme… - Molecular …, 2000 - Wiley Online Library
Several strains of the human opportunistic pathogen Pseudomonas aeruginosa infect
plants, nematodes and insects. Our laboratory has developed a multihost pathogenesis …
plants, nematodes and insects. Our laboratory has developed a multihost pathogenesis …
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