Introduction Syncope and palpitations as the only initial manifestations of myotonic
dystrophy type 1 (MD1) due to a CTG expansion of 50–100 repeats have not been reported …

Background and Objectives: A high risk of cardiac arrhythmias was reported in myotonic
dystrophy type 1 (DM1). The purpose of the study was to evaluate the risk of severe …

Carriage of interruptions in CTG repeats of the myotonic dystrophy protein kinase gene has
been associated with a broad spectrum of myotonic dystrophy type 1 (DM1) phenotypes …

Introduction Myotonic dystrophy is a multisystem disease associated with cardiac
abnormalities that are responsible for high morbidity and mortality. It commonly affects …

Aims Myotonic dystrophy type 1 (DM1) is caused by the expansion of CTG repeats (CTGn) in
the DM1 protein kinase (DMPK) gene while it remains unclear whether CTGn may be …

CTG triplet repeats of “normal” length in the myotonic dystrophy protein kinase (DMPK) gene
have been previously believed to be stable and new pathological expansion was not …

Myotonic dystrophy (DM) is a multisystemic disease caused by the expansion of a CTG
repeat, located in the 3′‐untranslated region of the DMPK gene. The number of CTG …

It is unclear if the severity of cardiac involvement in patients with myotonic dystrophy (MD) is
related to the size of the CTG‐repeat expansion. This open, uncontrolled, observational …

Background Cardiac involvement represents a major cause of morbidity and mortality in
patients with myotonic dystrophy type 1 (DM1) and prevention of sudden cardiac death …

Myotonic dystrophy type 1 (DM1) is the most prevalent inherited neuromuscular dystrophy in
adults. It is a multisystem disease with cardiac manifestations. Whilst these are well-defined …