Exploring the efficacy of tumor electric field therapy against glioblastoma: An in vivo and in vitro study

H Wu, L Yang, H Liu, D Zhou, D Chen… - CNS neuroscience & …, 2021 - Wiley Online Library
Aims Tumor electric fields therapy (TTFields) is emerging as a novel anti‐cancer
physiotherapy. Despite recent breakthroughs of TTFields in glioma treatment, the average …

Evaluation of a tumor electric field treatment system in a rat model of glioma

H Wu, C Wang, J Liu, D Zhou, D Chen… - CNS Neuroscience …, 2020 - Wiley Online Library
Objective Glioma is a devastating disease lacking effective treatment. Tumor electric field
therapy is emerging as a novel non‐invasive therapy. The current study evaluates the …

In Vivo Safety of Tumor Treating Fields (TTFields) Applied to the Torso

R Blatt, S Davidi, M Munster, A Shteingauz… - Frontiers in …, 2021 - frontiersin.org
Background Tumor Treating Fields (TTFields) therapy is a non-invasive, loco-regional, anti-
mitotic treatment modality that targets rapidly dividing cancerous cells, utilizing low intensity …

Advanced tumor electric fields therapy: A review of innovative research and development and prospect of application in glioblastoma

J Lan, Y Liu, J Chen, H Liu, Y Feng… - CNS Neuroscience & …, 2024 - Wiley Online Library
Background Glioblastoma multiforme (GBM) is an aggressive malignant tumor with a high
mortality rate and is the most prevalent primary intracranial tumor that remains incurable …

Tumor-treating fields in glioblastomas: past, present, and future

X Guo, X Yang, J Wu, H Yang, Y Li, J Li, Q Liu, C Wu… - Cancers, 2022 - mdpi.com
Simple Summary Glioblastoma (GBM) is the most common malignant primary brain tumor.
Although the standard of care, including maximal resection, concurrent radiotherapy with …

Tumor-treating fields: a fourth modality in cancer treatment

EJ Mun, HM Babiker, U Weinberg, ED Kirson… - Clinical Cancer …, 2018 - AACR
Despite major advances in therapy, cancer continues to be a leading cause of mortality. In
addition, toxicities of traditional therapies pose a significant challenge to tolerability and …

Tumor treating fields: concept, evidence and future

M Pless, U Weinberg - Expert opinion on investigational drugs, 2011 - Taylor & Francis
Introduction: Local control is fundamental, both for the curative as well as the palliative
treatment of cancer. Tumor treating fields (TTFields) are low intensity (1–2 V/cm) …

Tumor treating fields in neuro-oncology: integration of alternating electric fields therapy into promising treatment strategies

TR Berger, ET Wong - Chinese Clinical Oncology, 2021 - cco.amegroups.org
As the most recent innovation in cancer therapy that utilizes properties of the
electromagnetic spectrum, tumor treating fields (TTFields) are non-invasive alternating …

Tumor treating fields: a comprehensive overview of the underlying molecular mechanism

P Hong, N Kudulaiti, S Wu, J Nie… - Expert review of …, 2022 - Taylor & Francis
Introduction As a novel treatment modality, tumor treating fields (TTFields) exert low-
intensity, medium-frequency electric fields on tumor cells. TTFields' effectiveness and safety …

[HTML][HTML] Current status of the preclinical evaluation of alternating electric fields as a form of cancer therapy

C Pohling, H Nguyen, E Chang, KE Schubert, Y Nie… - …, 2023 - Elsevier
Exposing cancer cells to alternating electric fields of 100-300 kHz frequency and 1-4 V/cm
strength has been shown to significantly reduce cancer growth in cell culture and in human …