The interaction of gut microbiota and heart failure with preserved ejection fraction: from mechanism to potential therapies

W Yu, Y Jiang, H Xu, Y Zhou - Biomedicines, 2023 - mdpi.com
Heart failure with preserved ejection fraction (HFpEF) is a disease for which there is no
definite and effective treatment, and the number of patients is more than 50% of heart failure …

Gut microbiota in heart failure patients with preserved ejection fraction (GUMPTION study)

Z Huang, X Mei, Y Jiang, T Chen… - Frontiers in cardiovascular …, 2022 - frontiersin.org
Introduction: Heart failure with preserved ejection fraction (HFpEF) is associated with
disrupted intestinal epithelial function, resulting from intestinal congestion. Intestinal …

Gut microbiota in heart failure and related interventions

AT Chen, J Zhang, Y Zhang - Imeta, 2023 - Wiley Online Library
Heart failure (HF) is a sophisticated syndrome with structural or functional impairment of
ventricular filling or ejection of blood, either causing symptoms and signs or being …

Diet-Induced Microbiome's Impact on Heart Failure: A Double-Edged Sword

A Rodrigues, A Gonçalves, J Morais, R Araujo… - Nutrients, 2023 - mdpi.com
Heart failure (HF) is a debilitating disease with a significant clinical and economic impact
worldwide. Multiple factors seem to increase the risk of developing HF, such as …

Current understanding of gut microbiota alterations and related therapeutic intervention strategies in heart failure

X Chen, HY Li, XM Hu, Y Zhang… - Chinese medical journal, 2019 - mednexus.org
Objective: The purpose of this review is to stress the complicated interactions between the
microbiota and the development of heart failure. Moreover, the feasibility of modulating …

Gut microbiome-A potential mediator of pathogenesis in heart failure and its comorbidities: State-of-the-art review

P Mamic, T Chaikijurajai, WHW Tang - Journal of molecular and cellular …, 2021 - Elsevier
Gut microbiome (GMB) has been increasingly recognized as a contributor to development
and progression of heart failure (HF), immune-mediated subtypes of cardiomyopathy …

Recent advances on the role of gut microbiota in the development of heart failure by mediating immune metabolism

Y Huang, MW Ferrari, S Lin, Z Wang - Current Problems in Cardiology, 2024 - Elsevier
The association between gut microbiota and the development of heart failure has become a
research hotspot in recent years and the impact of gut microbiota on heart failure has …

The gut microbiome and heart failure: a better gut for a better heart

M Branchereau, R Burcelin, C Heymes - Reviews in Endocrine and …, 2019 - Springer
Despite the development of new drugs and therapeutic strategies, mortality and morbidity
related to heart failure (HF) remains high. It is also the leading cause of global mortality …

The Role of Gut Microbiota and the Potential Effects of Probiotics in Heart Failure

C Petruzziello, A Saviano, LL Manetti, N Macerola… - Medicina, 2024 - mdpi.com
Heart failure (HF) remains a significant global health challenge, affecting millions of
individuals worldwide and posing a substantial burden on healthcare systems. HF is a …

Role and effective therapeutic target of gut microbiota in heart failure

Q Jia, H Li, H Zhou, X Zhang, A Zhang… - Cardiovascular …, 2019 - Wiley Online Library
Although the mechanism of the occurrence and development of heart failure has been
continuously explored in the past ten years, the mortality and readmission rate of heart …