Shc family of docking proteins, ShcA, ShcB and ShcC, play roles in cellular signal
transduction by binding to phosphotyrosine residues of various activated receptor tyrosine …

Anaplastic lymphoma kinase (ALK) is a tyrosine kinase receptor originally identified as part
of the chimeric nucleophosmin-ALK protein in the t (2; 5) chromosomal rearrangement …

ShcC is a family member of the Shc docking proteins that possess two different
phosphotyrosine-binding motifs and conduct signals as Grb2-binding substrates of various …

The initial identification of the ALK gene, expressed as C‐terminal part of the transforming
fusion protein NPM‐ALK in the t (2; 5)(p23; q35) lymphoma‐associated chromosomal …

Anaplastic lymphoma kinase (ALK) is a novel neuronal orphan receptor tyrosine kinase that
is essentially and transiently expressed in specific regions of the central and peripheral …

The anaplastic lymphoma kinase (ALK) gene was initially identified as a fusion partner of the
nucleophosmin gene in anaplastic large‐cell lymphoma with t (2; 5)(p23; q35) translocation …

The (2; 5) translocation, found in many T-cell and null cell anaplastic large cell lymphomas
(ALCLs), creates a hybrid gene encoding the 80-kd NPM-ALK protein. Typically neoplastic …

Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase essentially and transiently
expressed in specific areas of the developing central and peripheral nervous systems. We …

Anaplastic lymphoma kinase (ALK) is a receptor-type protein tyrosine kinase that is
expressed preferentially in neurons of the central and peripheral nervous systems at late …

The normal functions of full‐length anaplastic lymphoma kinase (ALK) remain to be
completely elucidated. Although considered to be important in neural development, recent …