Melanoma develops from malignant transformations of the pigment-producing melanocytes.
If located in the basal layer of the skin epidermis, melanoma is referred to as cutaneous …

Cutaneous melanoma is the most common skin cancer with an incidence that has been
rapidly increasing in the past decades. Melanomas are among the most immunogenic …

Melanoma is one of the most aggressive types of skin cancer with rapidly increasing
incidence rate. The disease is largely considered incurable and the patients diagnosed with …

Melanoma is an immunogenic tumor whose relationship with immune cells resident in the
microenvironment significantly influences cancer cell proliferation, progression, and …

Melanocytes make up only a tiny proportion of the skin cellular milieu but have a major
impact on skin appearance as well as skin cancer risk by modulating skin pigmentation …

Melanoma, which evolves from melanocytes, is the most malignant skin cancer and is highly
fatal, although it only accounts for 4% of all skin cancers. Numerous studies have …

Abstract Learning Objectives After completing this course, the reader will be able to: Identify
the epidemiological evidence supporting the association of intermittent sun exposure with …

Melanin is a widely-distributed pigment in the biosphere. In the human adult, the
enzymatically-catalysed process of melanin generation is the exclusive prerogative of …

Cutaneous melanoma (CM) is a malignant tumor formed from pigment-producing cells
called melanocytes. It is one of the most aggressive and fatal forms of skin malignancy. In …

Over the past 3 decades, several breakthroughs have greatly expanded what is known
about melanocyte biology, relevant oncogenic mutations and deletions and amplifications in …