OBJECTIVE Intravital spectral imaging of the large, deeply situated nerves in the rat
peripheral nervous system (PNS) has not been well described. Here, the authors have …

Damage to the peripheral nervous system is surprisingly common and occurs primarily from
trauma or a complication of surgery. Although recovery of nerve function occurs in many mild …

Clinically available treatments are insufficient to achieve full functional recovery in large (>
3cm) peripheral nerve injuries (PNI). The objectives in this thesis were 1) to study often …

Background The rodent model is commonly used to study facial nerve injury. Because of the
exceptional regenerative capacity of the rodent facial nerve, it is essential to consider the …

Reconstructive surgery of the peripheral nerve has undergone major technical
improvements over the last decades, leading to a significant improvement in the clinical …

Regeneration of peripheral nerves after injury remains a challenge to both patients and
clinicians. Even after more than 70 years of microsurgery in this field, the outcome is often …

The study of peripheral nerve repair and regeneration is particularly relevant in the light of
the high clinical incidence of nerve lesions. However, the clinical outcome after nerve …

Peripheral nerve regeneration presents a significant clinical challenge and the current state
of the art using autografts to repair long peripheral nerve gaps is unsatisfactory. In this …

Transgenic mice whose axons and Schwann cells express fluorescent chromophores
enable new imaging techniques and augment concepts in developmental neurobiology. The …

Neural stem/progenitor cells (NSPCs) hold promise in neural tissue replacement therapy
after spinal cord injury. However, understanding the survival time of grafted NSPCs and …