Prevalence of integrase strand transfer inhibitors resistance mutations in integrase strand transfer inhibitors-naive and-experienced HIV-1 infected patients: a single …

MA De Francesco, I Izzo, M Properzi… - AIDS research and …, 2018 - liebertpub.com
Integrase strand transfer inhibitor (InSTI) resistance rates are low. However, genotypic
resistance test (GRT) is not routinely performed in many centers. The aim of this study is to …

Prevalence and determinants of resistance mutations in HIV‐1‐infected patients exposed to integrase inhibitors in a large Italian cohort

S Modica, B Rossetti, F Lombardi, F Lagi… - HIV …, 2019 - Wiley Online Library
Objectives The aim of the study was to analyse the prevalence of integrase resistance
mutations in integrase strand transfer inhibitor (INSTI)‐experienced HIV‐1‐infected patients …

Integrase strand transfer inhibitor (INSTI) genotypic resistance analysis in treatment-naive, INSTI free antiretroviral-experienced and INSTI-experienced Turkish …

M Sayan, FS Yildirim, S Akhan, I Karaoglan… - Current HIV …, 2022 - ingentaconnect.com
Background and Objective: Integrase strand transfer inhibitors (INSTIs) are currently the
standard of practice for first-line HIV therapy for most patients. We evaluated the mutations …

[HTML][HTML] Evaluation of HIV-1 integrase resistance emergence and evolution in patients treated with integrase inhibitors

R Scutari, C Alteri, I Vicenti, D Di Carlo… - Journal of Global …, 2020 - Elsevier
Objectives This study evaluated the emergence of mutations associated with integrase
strand transfer inhibitors (INSTI) resistance (INSTI-RMs) and the integrase evolution in …

Integrase strand transfer inhibitor resistance in integrase strand transfer inhibitor-naive persons

AJ Bailey, SY Rhee, RW Shafer - AIDS Research and Human …, 2021 - liebertpub.com
There has been no systematic review of the prevalence of transmitted integrase strand
transfer inhibitor (INSTI) resistance. We systematically searched the English-language …

Integrase strand transfer inhibitors (INSTIs) resistance mutations in HIV-1 infected Turkish patients

M Sayan, A Gündüz, G Ersöz, A İnan, A Deveci… - HIV clinical …, 2016 - Taylor & Francis
Objectives: Integrase strand transfer inhibitor (INSTI) is a new class of antiretroviral (ARV)
drugs designed to block the action of the integrase viral enzyme, which is responsible for …

Lack of HIV-1 integrase inhibitor resistance among 392 antiretroviral-naïve individuals in a tertiary care hospital in Beijing, China

L Liu, L Dai, J Yao, P Pan, L Li, Z Liu, X An, L Sun… - AIDS, 2019 - journals.lww.com
Reports of resistance to integrase strand transfer inhibitors (INSTIs) are now not uncommon.
We analyzed the HIV int gene from plasma of antiretroviral-naïve individuals during acute …

Resistance to integrase inhibitors: a national study in HIV-1-infected treatment-naive and-experienced patients

AG Marcelin, M Grude, C Charpentier… - Journal of …, 2019 - academic.oup.com
Objectives To describe integrase strand transfer inhibitor (INSTI) resistance profiles and
factors associated with resistance in antiretroviral-naive and-experienced patients failing an …

Integrase strand transfer inhibitor resistance mutations in antiretroviral therapy-naive and treatment-experienced HIV patients in South Korea

W Jeong, IY Jung, H Choi, JH Kim, H Seong… - AIDS research and …, 2019 - liebertpub.com
Updated guidelines for the treatment of antiretroviral therapy (ART)-negative patients with
HIV recommend integrase strand transfer inhibitor (INSTI)-based regimens. HIV patients are …

[HTML][HTML] Prevalence of integrase strand transfer inhibitors (INSTI) resistance mutations in Taiwan

SY Chang, PH Lin, CL Cheng, MY Chen, HY Sun… - Scientific reports, 2016 - nature.com
Antiretroviral therapy containing an integrase strand transfer inhibitor (INSTI) plus two NRTIs
has become the recommended treatment for antiretroviral-naive HIV-1-infected patients in …