Chemotherapy and tyrosine-kinase inhibitors for medullary thyroid cancer

J Hadoux, M Schlumberger - … Practice & Research Clinical Endocrinology & …, 2017 - Elsevier
Medullary thyroid cancer (MTC) represents 3% of all clinical thyroid cancers and arises from
thyroid C cells that produce calcitonin. Locally advanced or metastatic MTC requires a …

[HTML][HTML] Diagnostic characteristics, treatment patterns, and clinical outcomes for patients with advanced/metastatic medullary thyroid cancer

R Parikh, LM Hess, E Esterberg, NR Bhandari… - Thyroid Research, 2022 - Springer
Background Medullary thyroid cancer (MTC) accounts for approximately 1.6% of new cases
of thyroid cancer. The objective of this study was to describe patient characteristics …

Medullary thyroid cancer: medical management and follow-up

A Traugott, JF Moley - Current Treatment Options in Oncology, 2005 - Springer
Opinion statement Medullary thyroid carcinoma (MTC) is a neuroendocrine malignancy that
occurs in hereditary (25%) and sporadic (75%) clinical settings. MTC is present in all …

Medullary thyroid cancer: an update of new guidelines and recent developments

LS Wu, SA Roman, JA Sosa - Current opinion in oncology, 2011 - journals.lww.com
There have been several recent advances in the molecular biology, diagnosis, imaging, and
treatment options for MTC. Downstaging and treating metastatic disease more effectively …

Medullary thyroid cancer

YN You, V Lakhani, SA Wells… - Surgical Oncology …, 2006 - surgonc.theclinics.com
Medullary thyroid carcinoma (MTC) is a prototype disease in the rapidly emerging field of
molecular endocrine oncology. Since its recognition in 1959, MTC has distinguished itself …

Advances and controversies in the diagnosis and management of medullary thyroid carcinoma

HM Heshmati, H Gharib, JA van Heerden… - The American journal of …, 1997 - Elsevier
Recent advances in the diagnosis and treatment of medullary thyroid carcinoma (MTC) have
been significant, but some issues remain controversial. MTC may occur either as a …

Beyond RET: potential therapeutic approaches for advanced and metastatic medullary thyroid carcinoma

L Santarpia, L Ye, RF Gagel - Journal of internal medicine, 2009 - Wiley Online Library
Medullary thyroid carcinoma (MTC) is a rare calcitonin‐producing neuroendocrine tumour
that originates from the parafollicular C‐cells of the thyroid gland. The RET proto‐oncogene …

Medullary thyroid carcinoma: a 25-year perspective

X Matias-Guiu, R De Lellis - Endocrine pathology, 2014 - Springer
This article summarizes the major clinical, pathological, and molecular features of medullary
thyroid carcinoma (MTC), based on a review of the most significant advances in our …

[HTML][HTML] New drugs for medullary thyroid cancer: new promises?

C Spitzweg, JC Morris, KC Bible - Endocrine-Related Cancer, 2016 - erc.bioscientifica.com
Medullary thyroid cancer (MTC) is a rare tumor arising from the calcitonin-producing
parafollicular C cells of the thyroid gland, occurring either sporadically or alternatively in a …

Cellular signaling pathway alterations and potential targeted therapies for medullary thyroid carcinoma

S Giunti, A Antonelli, A Amorosi… - International journal of …, 2013 - Wiley Online Library
Parafollicular C‐cell‐derived medullary thyroid cancer (MTC) comprises 3% to 4% of all
thyroid cancers. While cytotoxic treatments have been shown to have limited efficacy …