Differential toxicity profile of ricin isoforms correlates with their glycosylation levels
P Sehgal, O Kumar, M Kameswararao, J Ravindran… - Toxicology, 2011 - Elsevier
Ricin is one of the most potent and deadly plant toxins from the seeds of Ricinus communis.
In view of its high toxicity, ricin is being used as an immunotoxin in cancer therapy. Ricin …
In view of its high toxicity, ricin is being used as an immunotoxin in cancer therapy. Ricin …
A novel neutralizing monoclonal antibody against both ricin toxin A and ricin toxin B, and application of a rapid sandwich enzyme-linked immunosorbent assay
J Guo, B Shen, J Feng, Y Sun, M Yu, M Hu - Hybridoma, 2006 - liebertpub.com
Two strains of neutralizing monoclonal antibodies (MAbs) anti-ricin, both B chain and A
chain, named 3D74 and 4C13, were generated efficiently. The two antibodies recognized …
chain, named 3D74 and 4C13, were generated efficiently. The two antibodies recognized …
Quantification of l-Abrine in Human and Rat Urine: A Biomarker for the Toxin Abrin
RC Johnson, Y Zhou, R Jain, SW Lemire… - Journal of analytical …, 2009 - academic.oup.com
Abrin is a toxic protein found in the jequirity seed. L-Abrine (N-methyl-tryptophan) is also
found in the jequirity seed and can be used as a biomarker for abrin exposure. Analysis of L …
found in the jequirity seed and can be used as a biomarker for abrin exposure. Analysis of L …
[HTML][HTML] Sensitive bioassay for detection of biologically active ricin in food
R Rasooly, X He - Journal of food protection, 2012 - Elsevier
The potential use of ricin as an agent of biological warfare highlights the need to develop
fast and effective methods to detect biologically active ricin. The current “gold standard” for …
fast and effective methods to detect biologically active ricin. The current “gold standard” for …
Probabilistic limit of detection for ricin identification using a shotgun proteomics assay
NC Heller, AM Garrett, ED Merkley… - Analytical …, 2019 - ACS Publications
Robust and highly specific methods for the detection of the protein toxin ricin are of interest
to the law enforcement community. In previous studies, methods based on liquid …
to the law enforcement community. In previous studies, methods based on liquid …
[PDF][PDF] 17Ricin and Related Toxins: Review and Perspective
CB Millard, RD LeClaire - Chemical Warfare Agents, 2008 - researchgate.net
The attractive and deadly Ricinus communis (castor bean plant) has been cultivated for its
commercial products, primarily castor seed oil, for at least 4000 years (Olsnes, 2004) …
commercial products, primarily castor seed oil, for at least 4000 years (Olsnes, 2004) …
[HTML][HTML] Simultaneous detection of ricin and abrin DNA by real-time PCR (qPCR)
E Felder, I Mossbrugger, M Lange, R Wölfel - Toxins, 2012 - mdpi.com
Ricin and abrin are two of the most potent plant toxins known and may be easily obtained in
high yield from the seeds using rather simple technology. As a result, both toxins are potent …
high yield from the seeds using rather simple technology. As a result, both toxins are potent …
Development of monoclonal antibodies specific for Ricinus agglutinins
DL Brandon, BJ Hernlem - Food and agricultural immunology, 2009 - Taylor & Francis
Ricin is a highly toxic, dichain ribosome-inactivating protein present in the seeds of Ricinus
communis (castor), grown principally as a source of high quality industrial lubricant and as …
communis (castor), grown principally as a source of high quality industrial lubricant and as …
Ricin poisoning: A review on contamination source, diagnosis, treatment, prevention and reporting of ricin poisoning
M Abbes, M Montana, C Curti, P Vanelle - Toxicon, 2021 - Elsevier
Introduction. Ricin, a toxic glycoprotein derived from the castor bean plant, is one of the most
potent poisons known in the world. Ricin intoxication is a fatal and uncommon medical …
potent poisons known in the world. Ricin intoxication is a fatal and uncommon medical …
Monoclonal Antibodies to Ricin: In Vitro Inhibition of Toxicity and Utility as Diagnostic Reagents
MT Dertzbaugh, CA Rossi, BM Paddle, M Hale… - Hybridoma, 2005 - liebertpub.com
Monoclonal antibodies (MAbs) against ricin toxin (RT) and its subunits were produced in
mice. The MAbs were initially selected based upon the ability to either bind ricin or the …
mice. The MAbs were initially selected based upon the ability to either bind ricin or the …