EGFR Mutations Detection in Non-small Cell Lung Cancer Tissues by Real-time PCR and DNA Sequencing.
Background Small molecule tyrosine kinase inhibitors (TKIs), such as gefitinib and erlotinib
that target the kinase domain of epidermal growth factor receptor (EGFR) are making …
that target the kinase domain of epidermal growth factor receptor (EGFR) are making …
广东地区非小细胞肺癌EGFR 基因的突变研究
陈慧娟， 喻长顺， 李洪波， 程俊峰， 鲁碧稳， 郑建树 - 分子诊断与治疗杂志, 2011 - cqvip.com
目的探讨广东地区非小细胞肺癌(NSCLC) 患者中EGFR 基因的突变情况.
方法用微分离富集肿瘤细胞, 采用QIAGENDNA 提取试剂盒提取基因组DNA, 通过PCR …
方法用微分离富集肿瘤细胞, 采用QIAGENDNA 提取试剂盒提取基因组DNA, 通过PCR …
Detection and its clinical significance of EGFR gene mutation and gene amplification in 187 patients with non-small cell lung cancer
背景与目的 现有的研究表明表皮生长因子受体 (EGFR) 相关信号通路在肺癌的发生和发展中起
重要作用. EGFR 酪氨酸激酶抑制剂 (EGFR-TKIs) 是目前针对 EGFR 治疗非小细胞肺癌 …
重要作用. EGFR 酪氨酸激酶抑制剂 (EGFR-TKIs) 是目前针对 EGFR 治疗非小细胞肺癌 …
Detection of EGFR mutations in circulating free DNA by PNA-mediated PCR clamping
HR Kim, SY Lee, DS Hyun, MK Lee, HK Lee… - Journal of Experimental …, 2013 - Springer
Background Epidermal growth factor receptor (EGFR)-activating mutations are major
determinants in predicting the tumor response to EGFR tyrosine kinase inhibitors in non …
determinants in predicting the tumor response to EGFR tyrosine kinase inhibitors in non …
[HTML][HTML] 晚期NSCLC 患者血清EGFR 基因突变状态的测定及意义
马玲， 刘莉， 张涛， 单莉 - Chinese Journal of Lung Cancer, 2013 - ncbi.nlm.nih.gov
背景与目的小分子酪氨酸激酶抑制剂(tyrosine kinase inhibitors, TKIs) 对于表皮生长因子受体(
epidermal growth factor receptor, EGFR) 基因突变的肺癌患者显示出良好的治疗效果 …
epidermal growth factor receptor, EGFR) 基因突变的肺癌患者显示出良好的治疗效果 …
Low correspondence of EGFR mutations in tumor tissue and paired serum of non-small-cell lung cancer patients
G Song, J Ren, L Zhang, L Di, Y Yuan, J Yu… - Chinese Journal of …, 2010 - Springer
Objective Epidermal growth factor receptor (EGFR) mutations are strong determinants of
tumor response to EGFR tyrosine kinase inhibitors in non-small-cell lung cancer (NSCLC) …
tumor response to EGFR tyrosine kinase inhibitors in non-small-cell lung cancer (NSCLC) …
Serum detection of epidermal growth factor receptor gene mutations using mutant-enriched sequencing in Chinese patients with advanced non-small cell lung cancer
B Jiang, F Liu, L Yang, W Zhang… - Journal of …, 2011 - journals.sagepub.com
Epidermal growth factor receptor gene (EGFR) mutations are among the best predictive
markers of the efficacy of EGFR tyrosine kinase inhibitor (EGFR-TKI) treatment. Mutations in …
markers of the efficacy of EGFR tyrosine kinase inhibitor (EGFR-TKI) treatment. Mutations in …
扩增耐突变系统对非小细胞肺癌表皮生长因子受体基因突变的检测
翁洁， 冯惊涛， 文芳， 胡建兵， 胡春宏 - 中华肿瘤防治杂志, 2012 - cqvip.com
目的: 探讨扩增耐突变系统检测非小细胞肺癌(NSCLC) 患者肿瘤组织EGFR
基因突变的应用价值. 方法: 选取70 例NSCLC 患者的病理切片, 提取基因组DNA …
基因突变的应用价值. 方法: 选取70 例NSCLC 患者的病理切片, 提取基因组DNA …
Comparison of three methods for detecting epidermal growth factor receptor mutations in plasma DNA samples of Chinese patients with advanced non-small cell lung …
QIN Ling, Z Wei, Z Li, LI Long-yun… - Chinese Medical …, 2011 - journals.lww.com
Background Epidermal growth factor receptor (EGFR) mutations can predict tumor response
to tyrosine kinase inhibitors (TKIs). Detecting EGFR mutations in plasma DNA samples in …
to tyrosine kinase inhibitors (TKIs). Detecting EGFR mutations in plasma DNA samples in …
A Rapid and Sensitive Method for Detection of the T790M Mutation of EGFR in Plasma DNA
H Kimura, S Nishikawa, H Koba, T Yoneda… - … Nucleic Acids in Serum …, 2016 - Springer
Epidermal growth factor receptor (EGFR) T790M mutation is associated with resistance to
EGFR tyrosine kinase inhibitors'(EGFR-TKIs) in non-small cell lung cancer (NSCLC). The …
EGFR tyrosine kinase inhibitors'(EGFR-TKIs) in non-small cell lung cancer (NSCLC). The …