Cytokine production induced by a 67‐kDa fimbrial protein from Porphyromonas gingivalis

N Hamada, K Watanabe, M Arai… - Oral microbiology …, 2002 - Wiley Online Library
Fimbriae have been reported to play an important role in the adherence of Porphyromonas
gingivalis to oral surfaces and possibly in triggering host responses. P. gingivalis ATCC …

Isolation and characterization of a minor fimbria from Porphyromonas gingivalis

N Hamada, HT Sojar, MI Cho, RJ Genco - Infection and immunity, 1996 - Am Soc Microbiol
We have discovered two distinctly different fimbriae expressed by the same Porphyromonas
gingivalis strain. The construction of a fimA mutant of P. gingivalis ATCC 33277 has …

Role of the Amino-Terminal Region ofPorphyromonas gingivalis Fimbriae in Adherence to Epithelial Cells

HT Sojar, Y Han, N Hamada, A Sharma… - Infection and …, 1999 - Am Soc Microbiol
Porphyromonas gingivalis fimbriae elicit many responses in eukaryotic cells, including
mitogenicity, cytokine production, epithelial cell invasion, and cellular immune response …

Distribution and immunochemical specificities of fimbriae of Porphyromonas gingivalis and related bacterial species

T Ogawa, T Mukai, K Yasuda… - Oral microbiology …, 1991 - Wiley Online Library
Rabbit polyclonal antibody (Poly‐1) and mouse monoclonal antibodies (mAbs) TO‐11, TO‐
14 and TO‐M1 specific for Porphyromonas gingivalis 381 fimbriae were prepared. Poly‐1 …

Porphyromonas gingivalis Fimbriae Bind to Cytokeratin of Epithelial Cells

HT Sojar, A Sharma, RJ Genco - Infection and immunity, 2002 - Am Soc Microbiol
The adherence of Porphyromonas gingivalis to host cells is likely a prerequisite step in the
pathogenesis of P. gingivalis-induced periodontal disease. P. gingivalis binds to and …

Isolation and characterization of fimbriae from a sparsely fimbriated strain of Porphyromonas gingivalis

HT Sojar, N Hamada, RJ Genco - Applied and environmental …, 1997 - Am Soc Microbiol
Porphyromonas gingivalis W50 (ATCC 53978) possesses the gene for fimbriae; however,
the surface-expressed fimbriae are sparse and have not been previously isolated and …

Purification of major fimbrial proteins of Porphyromonas gingivalis

JY Lee, HT Sojar, A Amano, RJ Genco - Protein expression and purification, 1995 - Elsevier
Binding of Porphyromonas gingivalis to pellicle-coated teeth is mediated to a large extent by
fimbrillin, a major structural subunit of fimbriae. A simple and efficient method for purifying …

Transformation and Expression of a ClonedfimA Gene in Porphyromonas gingivalis

Y Takahashi, D Kato, N Hamada… - Infection and …, 1999 - Am Soc Microbiol
The Porphyromonas gingivalis fimbria is an important virulence factor involved in the
adherence and colonization of the organism in the oral cavity. In this study, we transformed …

Expression of a functional Porphyromonas gingivalis fimbrillin polypeptide in Escherichia coli: purification, physicochemical and immunochemical characterization …

A Sharma, HT Sojar, JY Lee, RJ Genco - Infection and immunity, 1993 - Am Soc Microbiol
Fimbriae have been reported to play an important role in the adherence of Porphyromonas
gingivalis to oral surfaces and possibly in triggering host responses. A structural subunit of …

A role for fimbriae in Porphyromonas gingivalis invasion of oral epithelial cells

T Njoroge, RJ Genco, HT Sojar, N Hamada… - Infection and …, 1997 - Am Soc Microbiol
Isogenic mutants of Porphyromonas gingivalis which differ in the expression of fimbriae
were used to examine the contribution of fimbriae in invasion of a human oral epithelial cell …