Highlights•Surface receptor-mediated phage resistance often comes at a cost for
fitness.•Possible trade-offs may include attenuated virulence, and increased sensitivity to …

The current problems with increasing bacterial resistance to antibacterial therapies, resulting
in a growing frequency of incurable bacterial infections, necessitates the acceleration of …

Bacteriophages can influence the abundance, diversity, and evolution of bacterial
communities. Several bacteriophages have been reported to add virulence factors to their …

The rapid emergence and dissemination of multidrug-resistant (MDR) bacteria represents a
worldwide crisis concerning that humankind is re-entering the 'preantibiotics' era. Before the …

Bacteriophages (phage) that infect pathogenic bacteria often attach to surface receptors that
are coincidentally required for virulence. Receptor loss or modification through mutation …

In response to the emergence of pathogenic bacteria that cannot be treated with current
antibiotics, many researchers are revisiting the use of bacteriophages, or phages, to fight …

Highlights•Phages need to attach to a receptor on the bacterial surface to initiate infection.•It
is not common practice to identify these receptors before phage therapy use.•Identifying …

Treat phage like living antibiotics | Nature Microbiology Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain the …

Since their independent discovery by Frederick Twort in 1915 and Felix d'Herelle in 1917,
bacteriophages have captured the attention of scientists for more than a century. They are …

Bacteriophages (phages) are viruses that infect bacterial hosts, and since their discovery
over a century ago they have been primarily exploited to control bacterial populations and to …