[PDF][PDF] Codon usage bias is evolutionarily conserved
BMH Keng, OYW Chan, MHT Ling - Asia Pacific Journal of Life Sciences, 2014 - Citeseer
Codon usage bias (CUB) reflects the frequency distribution of codons usage in the genome.
Several studies suggest that CUB is based on the combinations, which are most chemically …
Several studies suggest that CUB is based on the combinations, which are most chemically …
Studies on the origin and evolution of codon bias
JC Biro - arXiv preprint arXiv:0807.3901, 2008 - arxiv.org
Background: There is a 3-fold redundancy in the Genetic Code; most amino acids are
encoded by more than one codon. These synonymous codons are not used equally; there is …
encoded by more than one codon. These synonymous codons are not used equally; there is …
Does codon bias have an evolutionary origin?
JC Biro - Theoretical Biology and Medical Modelling, 2008 - Springer
Background There is a 3-fold redundancy in the Genetic Code; most amino acids are
encoded by more than one codon. These synonymous codons are not used equally; there is …
encoded by more than one codon. These synonymous codons are not used equally; there is …
Variation in global codon usage bias among prokaryotic organisms is associated with their lifestyles
M Botzman, H Margalit - Genome biology, 2011 - Springer
Background It is widely acknowledged that synonymous codons are used unevenly among
genes in a genome. In organisms under translational selection, genes encoding highly …
genes in a genome. In organisms under translational selection, genes encoding highly …
Accounting for background nucleotide composition when measuring codon usage bias
JA Novembre - Molecular biology and evolution, 2002 - academic.oup.com
The phenomenon of codon usage bias has been important in the study of evolution because
it provides examples of weak selection working at the molecular level. During the last two …
it provides examples of weak selection working at the molecular level. During the last two …
Codon usage in twelve species of Drosophila
Background Codon usage bias (CUB), the uneven use of synonymous codons, is a
ubiquitous observation in virtually all organisms examined. The pattern of codon usage is …
ubiquitous observation in virtually all organisms examined. The pattern of codon usage is …
Avoidance of long mononucleotide repeats in codon pair usage
Protein is an essential component for life, and its synthesis is mediated by codons in any
organisms on earth. While some codons encode the same amino acid, their usage is often …
organisms on earth. While some codons encode the same amino acid, their usage is often …
Enhanced effective codon numbers to understand codon usage bias
RD Smith - Biosystems, 2022 - Elsevier
Codon usage bias is a well recognized phenomenon but the relative influence of its major
causes: G+ C content, mutational biases, and selection, are often difficult to disentangle …
causes: G+ C content, mutational biases, and selection, are often difficult to disentangle …
Codon Deviation Coefficient: a novel measure for estimating codon usage bias and its statistical significance
Background Genetic mutation, selective pressure for translational efficiency and accuracy,
level of gene expression, and protein function through natural selection are all believed to …
level of gene expression, and protein function through natural selection are all believed to …
Measuring codon usage bias
A Roth, M Anisimova… - … : mechanisms and models, 2012 - books.google.com
In protein-coding genes, the genetic code defines the translational mapping from nucleotide
triplets (or codons) to amino acids. Synonymous codons translate to the same amino acid …
triplets (or codons) to amino acids. Synonymous codons translate to the same amino acid …