Polo-like kinase 1 (PLK1) is a key regulator of eukaryotic cell division. During mitosis,
dynamic regulation of PLK1 is crucial for its roles in centrosome maturation, spindle …

Polo-like kinase 1 (Plk1) is a key regulator of cell division in eukaryotic cells. New
techniques, including the application of small-molecule inhibitors, have greatly expanded …

Abstract Polo-like kinase 1 (Plk1) is a key regulator of cell division in eukaryotic cells. In this
short review, we briefly summarized the well-established functions modulated by Plk1 during …

Polo-like kinase 1 (Plk1) has multiple important functions during M-phase progression. In
addition to a catalytic domain, Plk1 possesses a phosphopeptide-binding motif, the polo-box …

Polo-like kinase 1 (Plk1) functions as a key regulator of mitotic events by phosphorylating
substrate proteins on centrosomes, kinetochores, the mitotic spindle, and the midbody …

Polo-like kinase (Plk) 1 executes several essential functions to promote cell division. These
functions range from centrosome maturation in late G2 phase to the regulation of …

Mammalian polo-like kinase 1 (Plk1) has been studied intensively as a key regulator of
various cell cycle events that are critical for proper M-phase progression. The polo-box …

The master mitotic regulator, Polo-like kinase 1 (Plk1), is an essential gene for the correct
execution of cell division. Plk1 has strong clinical relevance, as it is considered a bona fide …

During cell division, duplicated genetic material is separated into two distinct daughter cells.
This process is essential for initial tissue formation during development and to maintain …

Cells are equipped with a diverse network of signaling and regulatory proteins that function
as cell cycle regulators and checkpoint proteins to ensure the proper progression of cell …