Serotonin (5-HT) 5-HT2A Receptor (5-HT2AR):5-HT2CR Imbalance in Medial Prefrontal Cortex Associates with Motor Impulsivity
NC Anastasio, SJ Stutz, LHL Fink… - ACS chemical …, 2015 - ACS Publications
A feature of multiple neuropsychiatric disorders is motor impulsivity. Recent studies have
implicated serotonin (5-HT) systems in medial prefrontal cortex (mPFC) in mediating …
implicated serotonin (5-HT) systems in medial prefrontal cortex (mPFC) in mediating …
Individual differences in impulsive action reflect variation in the cortical serotonin 5-HT2A receptor system
LHL Fink, NC Anastasio, RG Fox, KC Rice… - …, 2015 - nature.com
Impulsivity is an important feature of multiple neuropsychiatric disorders, and individual
variation in the degree of inherent impulsivity could play a role in the generation or …
variation in the degree of inherent impulsivity could play a role in the generation or …
Endogenous Serotonin 5-HT2A and 5-HT2C Receptors Associate in the Medial Prefrontal Cortex
AE Price, DJ Sholler, SJ Stutz… - ACS chemical …, 2019 - ACS Publications
The 5-HT2A receptor (5-HT2AR) and 5-HT2CR are localized to the same neurons within the
medial prefrontal cortex (mPFC), which regulates executive function, decision-making, and …
medial prefrontal cortex (mPFC), which regulates executive function, decision-making, and …
Pre-treatment with the mGlu2/3 receptor agonist LY379268 attenuates DOI-induced impulsive responding and regional c-Fos protein expression
L Wischhof, M Koch - Psychopharmacology, 2012 - Springer
Rationale Overactivation of serotonin (5-hydroxytryptamine, 5-HT) 2A receptors causes
impulsivity and attentional deficits. Since 5-HT 2A receptors are known to entertain …
impulsivity and attentional deficits. Since 5-HT 2A receptors are known to entertain …
Serotonin 1A receptors alter expression of movement representations
K Scullion, JA Boychuk, GR Yamakawa… - Journal of …, 2013 - Soc Neuroscience
Serotonin has a myriad of central functions involving mood, appetite, sleep, and memory
and while its release within the spinal cord is particularly important for generating …
and while its release within the spinal cord is particularly important for generating …
5-HT2A and 5-HT2C receptor antagonists have opposing effects on a measure of impulsivity: interactions with global 5-HT depletion
CA Winstanley, DEH Theobald, JW Dalley… - …, 2004 - Springer
Abstract Rationale Global serotonin (5-HT) depletion increases the number of premature
responses made on the five-choice serial reaction time task (5CSRT) in rats. In contrast, the …
responses made on the five-choice serial reaction time task (5CSRT) in rats. In contrast, the …
Serotonin 5-HT1A, 5-HT2A and dopamine D2 receptors strongly influence prefronto-hippocampal neural networks in alert mice: Contribution to the actions of …
Atypical antipsychotic drugs (APDs) used to treat positive and negative symptoms in
schizophrenia block serotonin receptors 5-HT 2A R and dopamine receptors D 2 R and …
schizophrenia block serotonin receptors 5-HT 2A R and dopamine receptors D 2 R and …
Opposing effects of 5-HT2A and 5-HT2C receptor antagonists in the rat and mouse on premature responding in the five-choice serial reaction time test
PJ Fletcher, M Tampakeras, J Sinyard, GA Higgins - Psychopharmacology, 2007 - Springer
Abstract Rationale Serotonin (5-HT) has been linked to impulsivity with recent data
suggesting that different receptor sub-types exert opposing influences on this behaviour …
suggesting that different receptor sub-types exert opposing influences on this behaviour …
Dissociable contribution of 5-HT1A and 5-HT2A receptors in the medial prefrontal cortex to different aspects of executive control such as impulsivity and compulsive …
M Carli, M Baviera, RW Invernizzi… - …, 2006 - nature.com
Abstract Serotonin (5-HT) receptors are increasingly recognized as major targets for
cognitive enhancement in schizophrenia. Several lines of evidence suggest a …
cognitive enhancement in schizophrenia. Several lines of evidence suggest a …
Intra-prefrontal 8-OH-DPAT and M100907 improve visuospatial attention and decrease impulsivity on the five-choice serial reaction time task in rats
CA Winstanley, Y Chudasama, JW Dalley… - …, 2003 - Springer
Rationale The central serotonergic systems are a major target for drugs used to treat
neuropsychiatric disorders such as depression and schizophrenia in which disruption of …
neuropsychiatric disorders such as depression and schizophrenia in which disruption of …