Impact of an Adenosine A2A Receptor Agonist and Antagonist on Binding of the Dopamine D2 Receptor Ligand [11C]raclopride in the Rodent Striatum
K Prasad, EFJ de Vries, JWA Sijbesma… - Molecular …, 2022 - ACS Publications
Adenosine A2A and dopamine D2 receptors in the basal ganglia form heterotetrameric
structures that are involved in the regulation of motor activity and neuropsychiatric functions …
structures that are involved in the regulation of motor activity and neuropsychiatric functions …
Effects of adenosine A2A receptor stimulation in vivo on dopamine D3 receptor agonist binding in the rat brain
M Hillefors, PB Hedlund, G von Euler - Biochemical pharmacology, 1999 - Elsevier
To investigate if adenosine A2A receptor stimulation in vivo modulates dopamine D3
receptor binding, we analyzed the effects of 2-[p-(carboxyethyl)-phenylethylamino]-5′-N …
receptor binding, we analyzed the effects of 2-[p-(carboxyethyl)-phenylethylamino]-5′-N …
[HTML][HTML] Effects of the adenosine A2A receptor antagonist KW6002 on the dopaminergic system, motor performance, and neuroinflammation in a rat model of …
K Prasad, EFJ de Vries, E van der Meiden… - …, 2024 - Elsevier
Abstract Adenosine A 2A-receptors (A 2A R) and dopamine D 2-receptors (D 2 R) are known
to work together in a synergistic manner. Inhibiting A 2A Rs by genetic or pharmacological …
to work together in a synergistic manner. Inhibiting A 2A Rs by genetic or pharmacological …
Stimulation of adenosine A1 receptors decreases in vivo dopamine D1 receptor binding of [11C]SCH23390 in the cat striatum revealed by positron emission …
Y Sakiyama, K Hatano, T Kato, T Tajima… - Annals of nuclear …, 2007 - Springer
It has been previously suggested that activation of adenosine A 1 receptor modulates
dopamine D 1 receptor binding in vitro, although the direct mechanism of this interaction in …
dopamine D 1 receptor binding in vitro, although the direct mechanism of this interaction in …
Effects of CGS 21680 in vivo on dopamine D2 agonist binding in the rat brain
M Hillefors-Berglund, PB Hedlund, G von Euler - Brain research, 1995 - Elsevier
To investigate whether adenosine A2a agonists modulate dopamine D2 receptor binding in
vivo, we have analyzed the effects of intraperitoneally administered 2-[p-(carboxyethyl) …
vivo, we have analyzed the effects of intraperitoneally administered 2-[p-(carboxyethyl) …
Adenosine A2A agonist CGS 21680 decreases the affinity of dopamine D2 receptors for dopamine in human striatum
Abstract Adenosine A2A receptors (A2AR) and dopamine D2 receptors (D2R) are highly
concentrated in the striatum, where they are co-localized and exert reciprocal antagonistic …
concentrated in the striatum, where they are co-localized and exert reciprocal antagonistic …
Adenosine A2A Receptor-Antagonist/Dopamine D2 Receptor-Agonist Bivalent Ligands as Pharmacological Tools to Detect A2A-D2 Receptor Heteromers
A Soriano, R Ventura, A Molero, R Hoen… - Journal of medicinal …, 2009 - ACS Publications
Adenosine A2A (A2AR) and dopamine D2 (D2R) receptors mediate the antagonism
between adenosinergic and dopaminergic transmission in striatopallidal GABAergic …
between adenosinergic and dopaminergic transmission in striatopallidal GABAergic …
[HTML][HTML] Effects of an Adenosine A2A Receptor Antagonist on Striatal Dopamine D2-Type Receptor Availability: A Randomized Control Study Using Positron Emission …
K Okita, K Kato, Y Shigemoto, N Sato… - Frontiers in …, 2021 - frontiersin.org
Introduction: Altered dopaminergic neurotransmission, especially in the functioning of
dopamine D2-type receptors, is considered central to the etiology of a variety of …
dopamine D2-type receptors, is considered central to the etiology of a variety of …
Adenosine A1 receptor‐mediated inhibition of dopamine release from rat striatal slices is modulated by D1 dopamine receptors
C O'Neill, BJ Nolan, A Macari… - European Journal of …, 2007 - Wiley Online Library
Dopamine release is regulated by presynaptic dopamine receptors and interactions
between adenosine and dopamine receptors have been well documented. In the present …
between adenosine and dopamine receptors have been well documented. In the present …
Increased in vivo [11C] raclopride binding to brain dopamine receptors in amphetamine-treated rats
MR Kilbourn, EF Domino - European journal of pharmacology, 2011 - Elsevier
The hypothesis that repeated daily doses of amphetamine increases the number of
available dopamine D2 receptors in vivo in rat striatum, and may enhance the response to …
available dopamine D2 receptors in vivo in rat striatum, and may enhance the response to …
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