Wild immunology

AB Pedersen, SA Babayan - Molecular ecology, 2011 - Wiley Online Library
In wild populations, individuals are regularly exposed to a wide range of pathogens. In this
context, organisms must elicit and regulate effective immune responses to protect their …

Mechanisms and methods in ecoimmunology: integrating within-organism and between-organism processes

CJ Downs, JS Adelman, GE Demas - American Zoologist, 2014 - academic.oup.com
Ecoimmunology utilizes techniques from traditionally laboratory-based disciplines—for
example, immunology, genomics, proteomics, neuroendocrinology, and cell biology—to …

Fitness consequences of immune responses: strengthening the empirical framework for ecoimmunology

AL Graham, DM Shuker, LC Pollitt… - Functional …, 2011 - Wiley Online Library
Ecoimmunologists aim to understand the costs, benefits, and net fitness consequences of
different strategies for immune defense. 2. Measuring the fitness consequences of immune …

A vertebrate cytokine primer for eco‐immunologists

LM Zimmerman, RM Bowden, LA Vogel - Functional Ecology, 2014 - Wiley Online Library
The field of eco‐immunology seeks to address the causes and consequences of natural
variation in immune responses. Recently, the development of more immunological …

Refining approaches and diversifying directions in ecoimmunology

LB Martin, ZM Weil, RJ Nelson - Integrative and Comparative …, 2006 - academic.oup.com
Ecoimmunologists have made many important discoveries about the immune systems of
wild animals including (1) immune activity is usually costly,(2) counter-intuitive decrements …

Pathogen pressure puts immune defense into perspective

NPC Horrocks, KD Matson, BI Tieleman - 2011 - academic.oup.com
The extent to which organisms can protect themselves from disease depends on both the
immune defenses they maintain and the pathogens they face. At the same time, immune …

The history of ecoimmunology and its integration with disease ecology

PM Brock, CC Murdock, LB Martin - 2014 - academic.oup.com
Ecoimmunology is an example of how fruitful integrative approaches to biology can be.
Since its emergence, ecoimmunology has sparked constructive debate on a wide range of …

Invertebrate ecological immunology

J Rolff, MT Siva-Jothy - Science, 2003 - science.org
Ecological immunology is a rapidly expanding field that examines the causes and
consequences of variation in immune function in the context of evolution and of ecology …

Into the wild: digging at immunology's evolutionary roots

RM Maizels, DH Nussey - Nature Immunology, 2013 - nature.com
The two pillars of modern immunology have been man and mouse; in both settings,
investigators seek to reduce complexity and control environmental conditions. However, the …

Immunity in a variable world

BP Lazzaro, TJ Little - … of the Royal Society B: Biological …, 2009 - royalsocietypublishing.org
Immune function is likely to be a critical determinant of an organism's fitness, yet most
natural animal and plant populations exhibit tremendous genetic variation for immune traits …