A wide agreement exists that environmental enrichment (EE) is most beneficial if introduced
early in life, but numerous studies reported that also aged animals remain responsive. As …

Brain aging is characterized by functional deterioration across multiple systems, associated
to a progressive decay of neural plasticity. Here, we explored environmental enrichment …

Previous studies from our lab have demonstrated that mild cognitive impairments identified
early in life are predictive of cognitive deficits that develop with age, suggesting that …

The human brain sustains a slow but progressive decline in function as it ages and these
changes are particularly profound in cognitive processing. A potential contributor to this …

This symposium presents work aimed at enhancing our understanding of the effects of
activity—physical, cognitive, and social—on cognitive and brain health under normative …

We assessed lifelong environmental enrichment effects on possible age-related
modifications in emotional behaviors, spatial memory acquisition, retrieval of recent and …

Age-associated changes in cognition are mirrored by impairments in cellular models of
memory and learning, such as long-term potentiation (LTP) and long-term depression (LTD) …

In rats, some cognitive capabilities, like spatial learning and memory, are preserved from
age-related decline by whole adult life enriched environment (EE) exposure. However, to …

In this monograph, we ask whether various kinds of intellectual, physical, and social
activities produce cognitive enrichment effects—that is, whether they improve cognitive …

Brain plasticity is the ability of the nervous system to change structurally and functionally in
response to experience. By shaping brain structure and function, experience leads to the …