Anticardiolipin antibody and anti-beta 2 glycoprotein I antibody assays

A Raby, K Moffat, M Crowther - Haemostasis: Methods and Protocols, 2013 - Springer
Antiphospholipid syndrome (APS) is an autoimmune disease and is a risk factor for a
number of clinical manifestations; the classic presentations include fetal death or thrombosis …

Associations among antiphospholipid antibody types, isotypes, and titers: an antiphospholipid syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS …

E Gkrouzman, R Willis, D Andrade, MG Tektonidou… - Laboratory …, 2023 - Elsevier
Several antiphospholipid antibody (aPL) profiles (“triple” and lupus anticoagulant [LA]
positivity) are associated with a higher risk for clinical manifestations of antiphospholipid …

Which are the best biological markers of the antiphospholipid syndrome?

LO Carreras, RR Forastiero, ME Martinuzzo - Journal of autoimmunity, 2000 - Elsevier
The diagnosis of antiphospholipid syndrome (APS) requires the presence of both clinical
and biological features. Due to the heterogeneity of anti-phospholipid antibodies (aPL) the …

Laboratory evaluation of anti-phospholipid syndrome: a preliminary prospective study of phosphatidylserine/prothrombin antibodies in an at-risk patient cohort

NM Heikal, TD Jaskowski, E Malmberg… - Clinical & …, 2015 - academic.oup.com
Summary Immunoglobulin (Ig) G/IgM autoantibodies to phosphatidylserine/prothrombin
(aPS/PT) were evaluated individually and in combination with criteria anti-phospholipid …

[PDF][PDF] Validation of a new panel of automated chemiluminescence assays for anticardiolipin antibodies in the screening for antiphospholipid syndrome

D Janek, L Slavik, J Ulehlova, V Krcova, A Hlusi… - Clin. Lab, 2016 - researchgate.net
SUMMARY Background: Antibodies Anticardiolipin (aCL) and anti-β2-glycoprotein I
(aβ2GPI) are two of three laboratory criteria of antiphospholipid syndrome (APS). All of …

Laboratory evaluation of antiphospholipid syndrome: an update on autoantibody testing

AE Tebo - Clinics in Laboratory Medicine, 2019 - labmed.theclinics.com
Antiphospholipid (aPL) syndrome (APS) is an autoimmune disorder characterized by
thrombosis and/or certain pregnancy-related complications in association with persistence …

Antiphospholipid ELISA: the state of the art

A Tincani, L Spatola, R Cattaneo, G Balestrieri - Lupus, 1996 - journals.sagepub.com
Despite the efforts made in the past to standardize Antiphospholipid (aPL) ELISA and the
high rate of concordance reached at that time, lJ in the following years different reports have …

The contribution of antiphosphatidylethanolamine antibodies in the diagnosis of the antiphospholipid syndrome

M Sanmarco, N Bardin - Lupus, 2012 - journals.sagepub.com
The diagnosis of seronegative antiphospholipid syndrome (APS) has been proposed for
patients with well-defined clinical APS but persistently negative for the routinely tested …

Antiphospholipid antibody ELISAs: Survey on the performance of clinical laboratories assessed by using lyophilized affinity-purified IgG with anticardiolipin and anti …

V Pengo, A Biasiolo, E Bison, V Chantarangkul… - Thrombosis research, 2007 - Elsevier
Lupus anticoagulant (LA) and anticardiolipin (aCL) antibodies are the classical tests used to
diagnose the antiphospholipid syndrome (APS). Unfortunately, since these are nonspecific …

Laboratory Evaluation of Antiphospholipid Syndrome: Is There a Role for Specific Noncriteria Antiphospholipid Antibody Tests?

N Heikal, TB Martins, SK White, R Willis… - American Journal of …, 2019 - academic.oup.com
Objectives Anti-β2 glycoprotein I domain I (anti-domain I) and anti-phosphatidylserine/
prothrombin (aPS/PT) antibodies are present in patients with antiphospholipid syndrome …