Radiometals in Imaging and Therapy: Highlighting Two Decades of Research

S Sharma, MK Pandey - Pharmaceuticals, 2023 - mdpi.com
The present article highlights the important progress made in the last two decades in the
fields of molecular imaging and radionuclide therapy. Advancements in radiometal-based …

Copper radiopharmaceuticals for theranostic applications

A Ahmedova, B Todorov, N Burdzhiev… - European Journal of …, 2018 - Elsevier
The growing advancement in nuclear medicine challenges researchers from several
different fields to integrate imaging and therapeutic modalities in a theranostic …

PET imaging with 89Zr: from radiochemistry to the clinic

MA Deri, BM Zeglis, LC Francesconi… - Nuclear medicine and …, 2013 - Elsevier
The advent of antibody-based cancer therapeutics has led to the concomitant rise in the
development of companion diagnostics for these therapies, particularly nuclear imaging …

A picture of modern Tc-99m radiopharmaceuticals: Production, chemistry, and applications in molecular imaging

A Boschi, L Uccelli, P Martini - Applied Sciences, 2019 - mdpi.com
Even today, techentium-99m represents the radionuclide of choice for diagnostic radio-
imaging applications. Its peculiar physical and chemical properties make it particularly …

Theranostic Nuclear Medicine with Gallium-68, Lutetium-177, Copper-64/67, Actinium-225, and Lead-212/203 Radionuclides: Focus Review

KA Morgan, SE Rudd, A Noor, PS Donnelly - Chemical Reviews, 2023 - ACS Publications
Molecular changes in malignant tissue can lead to an increase in the expression levels of
various proteins or receptors that can be used to target the disease. In oncology, diagnostic …

Radiometal complexes in molecular imaging and therapy

AM Rey - Current medicinal chemistry, 2010 - ingentaconnect.com
Radiometals have become increasingly important because of their use both for diagnostic
molecular imaging and therapy in Nuclear Medicine. The focus is on the study of …

Synthesis of DOTA-pyridine chelates for 64Cu coordination and radiolabeling of αMSH peptide

H Yang, F Gao, B McNeil, C Zhang, Z Yuan… - EJNMMI …, 2021 - Springer
Background 64 Cu is one of the few radioisotopes that can be used for both imaging and
therapy, enabling theranostics with identical chemical composition. Development of stable …

The radiopharmaceutical chemistry of technetium-99m

SM Rathmann, Z Ahmad, S Slikboer, HA Bilton… - Radiopharmaceutical …, 2019 - Springer
Abstract Technetium-99m (99m Tc) is a radiometal that has nearly ideal nuclear properties
for diagnostic nuclear medicine imaging, which has helped make it high impact and …

Radioactive main group and rare earth metals for imaging and therapy

TI Kostelnik, C Orvig - Chemical reviews, 2018 - ACS Publications
Radiometals possess an exceptional breadth of decay properties and have been applied to
medicine with great success for several decades. The majority of current clinical use …

Molecular imaging of cancer with copper-64 radiopharmaceuticals and positron emission tomography (PET)

M Shokeen, CJ Anderson - Accounts of chemical research, 2009 - ACS Publications
Molecular imaging has evolved over the past several years into an important tool for
diagnosing, understanding, and monitoring disease. Molecular imaging has distinguished …