[HTML][HTML] Recent progress in technetium-99m-labeled nanoparticles for molecular imaging and cancer therapy

S Mushtaq, A Bibi, JE Park, J Jeon - Nanomaterials, 2021 - mdpi.com
Nanotechnology has played a tremendous role in molecular imaging and cancer therapy.
Over the last decade, scientists have worked exceptionally to translate nanomedicine into …

New directions in the coordination chemistry of 99mTc: a reflection on technetium core structures and a strategy for new chelate design

SR Banerjee, KP Maresca, L Francesconi… - Nuclear medicine and …, 2005 - Elsevier
Bifunctional chelates offer a general approach for the linking of radioactive metal cations to
macromolecules. In the specific case of 99mTc, a variety of technologies have been …

The role of coordination chemistry in the development of target-specific radiopharmaceuticals

S Liu - Chemical Society Reviews, 2004 - pubs.rsc.org
There is a great current interest in developing target-specific radiopharmaceuticals for early
detection of diseases and radiotherapy of cancers. This critical review will focus on the role …

A practical guide to the construction of radiometallated bioconjugates for positron emission tomography

BM Zeglis, JS Lewis - Dalton Transactions, 2011 - pubs.rsc.org
Positron emission tomography (PET) has become a vital imaging modality in the diagnosis
and treatment of disease, most notably cancer. A wide array of small molecule PET …

Toward Organometallic 99mTc Imaging Agents: Synthesis of Water-Stable 99Tc–NHC Complexes

M Benz, B Spingler, R Alberto… - Journal of the American …, 2013 - ACS Publications
99TcVO2–NHC complexes containing monodentate and bidentate N-heterocyclic carbenes
(NHCs) have been prepared by the reactions of [TcO (glyc) 2]−(glyc= ethyleneglycolato) with …

Bifunctional coupling agents for radiolabeling of biomolecules and target-specific delivery of metallic radionuclides

S Liu - Advanced drug delivery reviews, 2008 - Elsevier
Receptor-based radiopharmaceuticals are of great current interest in molecular imaging and
radiotherapy of cancers, and provide a unique tool for target-specific delivery of …

The rise of metal radionuclides in medical imaging: copper-64, zirconium-89 and yttrium-86

OF Ikotun, SE Lapi - Future Medicinal Chemistry, 2011 - Taylor & Francis
Positron emission tomography, with its high sensitivity and resolution, is growing rapidly as
an imaging technology for the diagnosis of many disease states. The success of this …

Scandium-44: benefits of a long-lived PET radionuclide available from the 44Ti/44Sc generator system

F Roesch - Current radiopharmaceuticals, 2012 - ingentaconnect.com
44Ti/44Sc radionuclide generators are of interest for molecular imaging. The 3.97 hours half-
life of 44Sc and its high positron branching of 94.27% may stimulate the application of 44Sc …

[HTML][HTML] From Tc VII to Tc I; facile syntheses of bis-arene complexes [99 (m) Tc (arene) 2]+ from pertechnetate

M Benz, H Braband, P Schmutz, J Halter, R Alberto - Chemical science, 2015 - pubs.rsc.org
Bis-arene complexes of technetium represent a fundamental class of organometallic
compounds. Due to complex synthetic routes, no detailed insights into their properties have …

[HTML][HTML] AAZTA-derived chelators for the design of innovative radiopharmaceuticals with theranostic applications

C Fersing, N Masurier, L Rubira, E Deshayes… - Pharmaceuticals, 2022 - mdpi.com
With the development of 68Ga and 177Lu radiochemistry, theranostic approaches in
modern nuclear medicine enabling patient-centered personalized medicine applications …