Background Information on particle deposition, retention, and clearance is important when
evaluating the risk of inhaled nanomaterials to human health. The revised Organization …

Background Information on particle deposition, retention and clearance are important for the
evaluation of the risk of inhaled nanomaterials to human health. Recent revised OECD …

Recently revised OECD inhalation toxicity testing guidelines require measurements of lung
burden immediately after and for periods following exposure for nanomaterials. Lung burden …

Background Inhalation exposure to nanomaterials in workplaces can include a mixture of
multiple nanoparticles. Such ambient nanoparticles can be of high dissolution or low …

Background Inhalative nanocarriers for local or systemic therapy are promising. Gold
nanoparticles (AuNP) have been widely considered as candidate material. Knowledge …

Background Toxicokinetics of nanomaterials, including studies on the absorption,
distribution, metabolism, and elimination of nanomaterials, are essential in assessing their …

Background Gold nanoparticles are widely used in consumer products, including cosmetics,
food packaging, beverages, toothpaste, automobiles, and lubricants. With this increase in …

Abstract As encouraged by Toxicity Testing in the 21st Century, researchers increasingly
apply high-throughput in vitro approaches to identify and characterize nanoparticle hazards …

The increasing use of gold nanoparticles leads to a possible increase of exposure by
inhalation. Therefore, we have studied the deposition patterns of inhaled 20 nm gold …

Background The lung epithelial tissue barrier represents the main portal for entry of inhaled
nanoparticles (NPs) into the systemic circulation. Thus great efforts are currently being made …