New developments in our understanding of vitamin D metabolism, action and treatment

S Christakos, S Li, J De La Cruz, DD Bikle - Metabolism, 2019 - Elsevier
Although vitamin D has been reported to have pleiotropic effects including effects on the
immune system and on cancer progression, the principal action of vitamin D is the …

Vitamin D and the immune system

C Aranow - Journal of investigative medicine, 2011 - journals.sagepub.com
It is now clear that vitamin D has important roles in addition to its classic effects on calcium
and bone homeostasis. As the vitamin D receptor is expressed on immune cells (B cells, T …

100 years of vitamin D: Historical aspects of vitamin D

G Jones - Endocrine Connections, 2022 - ec.bioscientifica.com
Vitamin D has many physiological functions including upregulation of intestinal calcium and
phosphate absorption, mobilization of bone resorption, renal reabsorption of calcium as well …

Vitamin D supplementation guidelines

P Pludowski, MF Holick, WB Grant… - The Journal of steroid …, 2018 - Elsevier
Research carried out during the past two-decades extended the understanding of actions of
vitamin D, from regulating calcium and phosphate absorption and bone metabolism to many …

The pleiotropic actions of vitamin D

R Lin, JH White - Bioessays, 2004 - Wiley Online Library
General knowledge of the role of vitamin D3 in human physiology has been shaped by its
discovery as a preventive agent of nutritional rickets, a defect in bone development due to …

The high prevalence of inadequate serum vitamin D levels and implications for bone health

JY Reginster - Current medical research and opinion, 2005 - Taylor & Francis
Background: Inadequate serum vitamin D is associated with secondary
hyperparathyroidism, increased bone turnover, and bone loss, which increase fracture risk …

Current perspectives on vitamin D, immune system, and chronic diseases

MC Borges, LA Martini, MM Rogero - Nutrition, 2011 - Elsevier
Accumulating data support that vitamin D possesses several biological and molecular
actions apart from its role in calcium homeostasis. Immune cells express vitamin D receptor …

[HTML][HTML] Vitamin D: deficiency, sufficiency and toxicity

F Alshahrani, N Aljohani - Nutrients, 2013 - mdpi.com
The plethora of vitamin D studies over the recent years highlight the pleomorphic effects of
vitamin D outside its conventional role in calcium and bone homeostasis. Vitamin D …