Clinical, radiologic, and immunologic features distinguish neuromyelitis optica from other
severe cases of multiple sclerosis. NMO-IgG is the first specific marker for a central nervous …

NMO-IgG, the auto-antibody specific to the aquaporin-4 (AQP4) water channel associated
with the autoimmune inflammatory disease neuromyelitis optica (NMO), is considered to be …

Neuromyelitis optica (NMO) is an inflammatory demyelinating disease that selectively affects
optic nerves and spinal cord. It is considered a severe variant of multiple sclerosis (MS), and …

Background Neuromyelitis optica (NMO)–IgG is a specific autoantibody marker for NMO. It
binds selectively to aquaporin 4 (AQP4), which is highly concentrated in astrocytic foot …

Neuromyelitis optica (NMO) is an autoimmune, demyelinating disorder of the central
nervous system (CNS) with typical clinical manifestations of optic neuritis and acute …

Objective Antibodies to cell surface central nervous system proteins help to diagnose
conditions which often respond to immunotherapies. The assessment of antibody assays …

Abstract Background Neuromyelitis optica (NMO, Devic disease) is a severely disabling
autoimmune disorder of the CNS, which was considered a subtype of multiple sclerosis (MS) …

Neuromyelitis optica (NMO) is a rare autoimmune disorder, distinct from multiple sclerosis,
causing inflammatory lesions in the optic nerves and spinal cord. An autoantibody (NMO …

Background The involvement of astrocyte water channel aquaporin-4 (AQP4) in
autoimmune diseases of the central nervous system has been suggested following the …

Neuromyelitis optica spectrum disorder (NMOSD) is an uncommon antibody-mediated
disease of the central nervous system. Long segments of spinal cord inflammation (myelitis) …