Background The involvement of astrocyte water channel aquaporin-4 (AQP4) in
autoimmune diseases of the central nervous system has been suggested following the …

Background: Antibodies to aquaporin-4 (AQP4-Ab), known as NMO-IgG, are a sensitive and
specific marker for neuromyelitis optica (NMO). Methods: To develop an enzyme-linked …

Neuromyelitis optica spectrum disorder (NMOSD) is an uncommon antibody-mediated
disease of the central nervous system. Long segments of spinal cord inflammation (myelitis) …

Neuromyelitis optica (NMO) is an inflammatory demyelinating disease that principally targets
the optic nerves and spinal cord and often leads to severe disability and occasionally life …

Antibodies to aquaporin‐4 (called NMO‐IgG or AQP4‐Ab) constitute a sensitive and highly
specific serum marker of neuromyelitis optica (NMO) that can facilitate the differential …

Abstract Aquaporin-4 (AQP4) has recently been implicated in the pathogenesis of
neuromyelitis optica (NMO) where it has been identified as the first defined autoantigen …

Autoantibodies against astrocyte water channel aquaporin-4 (AQP4) are thought to be
pathogenic in neuromyelitis optica (NMO). Prior work has suggested that a key component …

We have compared five different assays for antibodies to aquaporin-4 in 181 cases of
suspected Neuromyelitis optica spectrum disorders (NMOSD) and 253 controls to assess …

Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory disorder of the central
nervous system (CNS) mostly manifesting as optic neuritis and/or myelitis, which are …

Autoantibodies against astrocyte water channel aquaporin-4 (AQP4) are highly specific for
the neuroinflammatory disease neuromyelitis optica (NMO). We measured the binding of …