Background An update of evidence-based guidelines concerning liberation from mechanical
ventilation is needed as new evidence has become available. The American College of …

Background This clinical practice guideline addresses six questions related to liberation
from mechanical ventilation in critically ill adults. It is the result of a collaborative effort …

Background: Interventions that lead to earlier liberation from mechanical ventilation can
improve patient outcomes. This guideline, a collaborative effort between the American …

Background: This clinical practice guideline addresses six questions related to liberation
from mechanical ventilation in critically ill adults. It is the result of a collaborative effort …

Patients require mechanical ventilatory support when the ventilatory and/or gas exchange
capabilities of their respiratory system fail. This failure can be the result of processes both …

Importance Daily spontaneous breathing trials (SBTs) are the best approach to determine
whether patients are ready for disconnection from mechanical ventilation, but mode and …

Importance In adults in whom weaning from invasive mechanical ventilation is difficult,
noninvasive ventilation may facilitate early liberation, but there is uncertainty about its …

Health-care professionals (HCPs) can provide protocol-based care that has a measurable
impact on critically ill patients beyond their liberation from mechanical ventilation (MV) …

Purpose To summarize the evidence comparing noninvasive positive pressure ventilation
(NPPV) and invasive positive pressure ventilation (IPPV) weaning on mortality, ventilator …

There is an interesting body of clinical research in the discontinuation of mechanical
ventilation. Recent randomized controlled studies provide high-level evidence for the best …