This book provides a comprehensive, up-to-date review of the structure, biology, and
molecular interactions of proteoglycans, consolidating into a single source research using …

Heparan sulfate proteoglycans are complex molecules composed of a core protein with
covalently attached glycosaminoglycan chains. While the protein part determines …

Proteoglycans are abundant components of the cell surface and extracellular matrix that
mediate critical interactions between cells and their environment. They play a variety of …

Proteoglycans are produced by most eukaryotic cells and are versatile components of
pericellular and extracellular matrices. They belong to many different protein families. Their …

The molecular mechanisms that determine the interactions between cells and their
microenvironment are of central importance to the normal development and function of …

Heparan sulfate chains have markedly heterogeneous structures in which distinct patterns of
sulfation determine the binding specificity for ligand proteins. These “fine structures” of …

Heparan sulfate is a regulatory polysaccharide. It modulates specific growth factor‐receptor
interactions, accelerates the formation of specific proteinase‐proteinase inhibitor complexes …

Heparan sulfate proteoglycans are a remarkably diverse family of glycosaminoglycan-
bearing protein cores that include the syndecans, the glypicans, perlecan, agrin, and …

This issue of Seminars in Cell and Developmental Biology contains a number of articles
reviewing the cellular functions of proteoglycans. Proteoglycans are proteins, substituted …

In this special issue of Matrix Biology centered on proteoglycan biology we have assembled
a blend of articles focused on the state-of-the-art of proteoglycanology. The field has greatly …