Steroid-induced posterior subcapsular cataracts (PSCs) exhibit three main distinctive
characteristics:(i) association only with steroids possessing glucocorticoid activity,(ii) …

The prevailing view regarding the mechanism of steroid cataract formation holds that
glucocorticoids are covalently bound to lens proteins resulting in destabilization of the …

Prolonged use of glucocorticoids is a significant risk factor for the development of posterior
subcapsular cataract. This places restrictions on the use of glucocorticoids in the treatment …

The association linking corticosteroid therapy with the development of posterior subcapsular
cataracts has been well documented. These drugs are widely used therapeutically …

purpose. Prolonged use of glucocorticoids (GCs) can lead to cataract formation. Lens GC
responses have been difficult to elucidate. A previous study showed the presence of the …

A frequent manifestation of long-term glucocorticoid administration is the occurrence of
posterior subcapsular cataracts. The molecular basis for this effect has not yet been …

The injection of glucocorticoids into the vitreous chamber of the rabbit eye results in the
development of posterior subcapsular opacities. These lesions appear to be similar in …

• While the cataractogenic effects of corticosteroids are beyond dispute, disagreement exists
concerning effects of total dose, intensity of dose, and duration of administration on cataract …

OBJECTIVE:: Longitudinal associations between inhaled and oral corticosteroid use and 10-
year incident cataract were examined. DESIGN: Population-based cohort study …

Background The use of systemic corticosteroids is a risk factor for the development of
posterior subcapsular cataracts, but the association between inhaled corticosteroids and …