Cdc48p/p97 is a highly conserved essential AAA protein that is required for many cellular
processes, and is identified as a causative gene for an autosomal dominant human disorder …

The chaperone-related, ubiquitin-selective AAA (ATPase associated with a variety of cellular
activities) protein Cdc48 (also known as TER94, p97 and VCP) is a key regulator of …

Objectives CDC45 is the core component of CMG (CDC45‐MCMs‐GINS) complex that plays
important role in the initial step of DNA replication in eukaryotic cells. The expression level of …

The Cdc (cell division cycle) 45 protein has a central role in the regulation of the initiation
and elongation stages of eukaryotic chromosomal DNA replication. In addition, it is the main …

Abstract Cdc48 (alias p97, VCP) is an important motor and regulator for the turnover of
ubiquitylated proteins, both in proteasomal degradation and in nonproteolytic pathways. The …

The phosphatase Cdc25A was shown to be a target of the transcription factor c-Myc. Myc-
induced apoptosis appeared dependent on Cdc25A expression and Cdc25A over …

Background Cells control progression through late mitosis by regulating Cdc20 and Cdh1,
the two mitotic activators of the anaphase-promoting complex (APC). The control of Cdc20 …

Cell division cycle 25 A (Cdc25A), a dual-specificity protein phosphatase, is one of the most
crucial cell cycle regulators, which removes the inhibitory phosphorylation in cyclin …

We show that caspase-3 cleaves Cdc6 at D290/S and D442/G sites, producing p32-tCdc6
(truncated Cdc6) and p49-tCdc6, respectively, during etoposide-or tumor necrosis factor …

The highly conserved AAA ATPase p97 (VCP/CDC48) has well-established roles in cell
cycle progression, proteasome degradation and membrane dynamics. Gene disruption in …