Leptin and the risk of Barrett's oesophagus
Background: Obesity is associated with increased risks of Barrett's oesophagus and
oesophageal adenocarcinoma. Alterations in serum leptin and adiponectin, obesity-related …
oesophageal adenocarcinoma. Alterations in serum leptin and adiponectin, obesity-related …
Serum leptin and adiponectin levels and risk of Barrett's esophagus and intestinal metaplasia of the gastroesophageal junction
OM Thompson, SAA Beresford, EA Kirk, MP Bronner… - …, 2010 - Wiley Online Library
Persons diagnosed with Barrett's esophagus (BE) are at increased risk of developing
esophageal adenocarcinoma (EA). Obesity is a major risk factor for both BE and EA. The …
esophageal adenocarcinoma (EA). Obesity is a major risk factor for both BE and EA. The …
The association of gastric leptin with oesophageal inflammation and metaplasia
Background: Gastro-oesophageal reflux disease complications may reflect imbalances
between protective and injurious factors. Through its effects on cell growth, leptin may …
between protective and injurious factors. Through its effects on cell growth, leptin may …
Association between markers of obesity and progression from Barrett's esophagus to esophageal adenocarcinoma
C Duggan, L Onstad, S Hardikar, PL Blount… - Clinical …, 2013 - Elsevier
Background & Aims Individuals with Barrett's esophagus (BE) have an increased risk of
developing esophageal adenocarcinoma (EA). Obesity contributes to the development of BE …
developing esophageal adenocarcinoma (EA). Obesity contributes to the development of BE …
The role of obesity in oesophageal cancer development
E Long, ILP Beales - Therapeutic advances in …, 2014 - journals.sagepub.com
The incidence of oesophageal adenocarcinoma has increased dramatically in the
developed world in the last half century. Over approximately the same period there has been …
developed world in the last half century. Over approximately the same period there has been …
Leptin and gastro‐intestinal malignancies
JM Howard, GP Pidgeon, JV Reynolds - Obesity Reviews, 2010 - Wiley Online Library
Obesity is a well‐established risk factor for the development and mortality from several
cancers, including adenocarcinoma of the oesophagus, oesophago‐gastric junction and …
cancers, including adenocarcinoma of the oesophagus, oesophago‐gastric junction and …
Leptin stimulates proliferation and inhibits apoptosis in Barrett's esophageal adenocarcinoma cells by cyclooxygenase-2-dependent, prostaglandin-E2-mediated …
O Ogunwobi, G Mutungi, ILP Beales - Endocrinology, 2006 - academic.oup.com
Obesity is an important risk factor for esophageal adenocarcinoma (EAC), and elevated
serum leptin is characteristic of obesity. We hypothesized that leptin may have biological …
serum leptin is characteristic of obesity. We hypothesized that leptin may have biological …
[HTML][HTML] Pathophysiological mechanisms linking obesity and esophageal adenocarcinoma
L Alexandre, E Long, ILP Beales - World journal of gastrointestinal …, 2014 - ncbi.nlm.nih.gov
In recent decades there has been a dramatic rise in the incidence of esophageal
adenocarcinoma (EAC) in the developed world. Over approximately the same period there …
adenocarcinoma (EAC) in the developed world. Over approximately the same period there …
Association of serum levels of adipokines and insulin with risk of Barrett's esophagus: a systematic review and meta-analysis
AK Chandar, S Devanna, C Lu, S Singh, K Greer… - Clinical …, 2015 - Elsevier
Background & Aims Metabolically active visceral fat may be associated with esophageal
inflammation, metaplasia, and neoplasia. We performed a meta-analysis to evaluate the …
inflammation, metaplasia, and neoplasia. We performed a meta-analysis to evaluate the …
Circulating leptin and inflammatory response in esophageal cancer, esophageal cancer-related cachexia–anorexia syndrome (CAS) and non-malignant CAS of the …
D Diakowska, M Krzystek-Korpacka… - Cytokine, 2010 - Elsevier
We investigated the association between esophageal cancer and cachexia–anorexia
syndrome (CAS) of the alimentary tract and leptin, an adipocytokine crucial for body weight …
syndrome (CAS) of the alimentary tract and leptin, an adipocytokine crucial for body weight …