Bioinformatics analysis and epitope screening of a potential vaccine antigen TolB from Acinetobacter baumannii outer membrane protein

X Song, H Zhang, D Zhang, W Xie, G Zhao - Infection, Genetics and …, 2018 - Elsevier
The clinical isolation rate of multidrug-resistant or pan-resistant Acinetobacter baumannii (A.
baumannii) is increasing, resulting that optional antibiotics are very limited in clinical …

[HTML][HTML] A bioinformatics approach to introduce novel multi-epitope vaccines against Acinetobacter baumannii retrieved from immunogenic extracellular loops of outer …

M Meskini, NN Goodarzi, S Fereshteh… - Informatics in Medicine …, 2022 - Elsevier
Increasing antibiotic resistance of Acinetobacter baumannii highlights the urgent need to
develop an effective vaccine to combat it. Despite all efforts, no approved vaccine against …

Putative novel outer membrane antigens multi-epitope DNA vaccine candidates identified by Immunoinformatic approaches to control Acinetobacter baumannii

NS Tabibpour, A Doosti, A Sharifzadeh - BMC immunology, 2023 - Springer
Multi-epitope polypeptide vaccines, a fusion protein, often have a string-of-beads system
composed of various specific peptide epitopes, potential adjuvants, and linkers. When …

Antibiotic Resistance Determinant-Focused Acinetobacter baumannii Vaccine Designed Using Reverse Vaccinology

Z Ni, Y Chen, E Ong, Y He - International journal of molecular sciences, 2017 - mdpi.com
As one of the most influential and troublesome human pathogens, Acinetobacter baumannii
(A. baumannii) has emerged with many multidrug-resistant strains. After collecting 33 …

Vaccinomics to Design a Multi-Epitopes Vaccine for Acinetobacter baumannii

M Ud-Din, A Albutti, A Ullah, S Ismail, S Ahmad… - International Journal of …, 2022 - mdpi.com
Antibiotic resistance (AR) is the result of microbes' natural evolution to withstand the action
of antibiotics used against them. AR is rising to a high level across the globe, and novel …

[HTML][HTML] Putative novel B-cell vaccine candidates identified by reverse vaccinology and genomics approaches to control Acinetobacter baumannii serotypes

S Beiranvand, A Doosti, SA Mirzaei - Infection, Genetics and Evolution, 2021 - Elsevier
In the last decade, Multi-drug resistance (MDR)-associated infections of Acinetobacter
baumannii have grown worldwide. A cost-effective preventative strategy against this …

Identification of novel vaccine candidates against Acinetobacter baumannii using reverse vaccinology

MH Chiang, WC Sung, SP Lien, YZ Chen… - Human vaccines & …, 2015 - Taylor & Francis
Acinetobacter baumannii (Ab) is a global emerging bacterium causing nosocomial infections
such as pneumonia, meningitis, bacteremia and soft tissue infections especially in intensive …

In silico design of an immunogen against Acinetobacter baumannii based on a novel model for native structure of outer membrane protein A

A Jahangiri, I Rasooli, P Owlia, AAI Fooladi… - Microbial …, 2017 - Elsevier
Outer membrane protein A (OmpA) is the most promising vaccine candidate against one of
the most successful nosocomial pathogens, A. baumannii. Despite advantages of the …

Acinetobacter baumannii subunit vaccines: recent progress and challenges

YT Lau, HS Tan - Critical reviews in microbiology, 2023 - Taylor & Francis
Acinetobacter baumannii is a Gram-negative, opportunistic pathogen that causes
nosocomial infection with a high mortality rate in immunocompromised individuals. With the …

New putative vaccine candidates against Acinetobacter baumannii using the reverse vaccinology method

S Fereshteh, S Abdoli, F Shahcheraghi, S Ajdary… - Microbial …, 2020 - Elsevier
Infections caused by multi-drug resistance Acinetobacter baumannii are increasing
worldwide. Discovery of the vaccine against this bacterium as a cost-effective and preventive …