Background: Respiratory distress due to inadequate lung liquid clearance is a significant
problem in infants delivered late preterm or early term, especially by elective cesarean …

Introduction Lung fluid clearance is essential for successful postnatal pulmonary adaptation.
The epithelial sodium channel (ENaC) and Na‐K‐ATPase, induced by serum‐and …

Abstract Background Antenatal glucocorticoids (GCs) reduce respiratory distress syndrome
(RDS) in preterm infants and are associated with reduced lung liquid content. Our aim was …

Background: The airway epithelial sodium channel (ENaC) is rate limiting for postnatal
alveolar fluid clearance. Increased lung water content is a feature of respiratory distress …

Purpose Glucocorticoids and progesterone exert stimulatory effects on epithelial Na+
transport, including increased mRNA expression of the participating ion transporters …

BACKGROUND: Glucocorticoids have profound effects on lung maturation and function. In
in vitro and animal models, they induce epithelial sodium channels (ENaCs) in the airway …

Preterm infants frequently suffer from respiratory distress syndrome (RDS), possibly due to
lower expression of epithelial Na+ channels (ENaC). RDS incidence is sex-specific …

Rationale: Fetal lung liquid secretion is coupled with chloride transport into the lung lumen.
The postnatal clearance of lung liquid is dependent on osmotic force generated by active …

We tested the hypothesis that interleukin (IL)-1β-induced cortisol synthesis stimulates distal
lung fluid absorption in fetal guinea pigs via induction of serum-and glucocorticoid-regulated …

At birth, lung fluid clearance is coupled to Na+ transport through epithelial Na+ channels
(ENaC) in the distal lung epithelium. We evaluated the effect of postnatal glucocorticoids …