Previous expression quantitative trait loci (eQTL) studies have performed genetic
association studies for gene expression, but most of these studies examined lymphoblastoid …

Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality
worldwide. COPD is thought to arise from the interaction of environmental exposures and …

Lung cancer is a leading cause of cancer death and disease burden in many countries.
Understanding of the biological pathways involved in lung cancer aetiology is required to …

Background Lung function measures reflect the physiological state of the lung, and are
essential to the diagnosis of chronic obstructive pulmonary disease (COPD). The SpiroMeta …

Spirometric measures of pulmonary function have been shown to be highly heritable and
evidence for major genes influencing forced expiratory volume in 1 s (FEV1) and forced vital …

Decreased spirometric indices are characteristic of asthma and other respiratory diseases.
The aim of this study was to investigate the genetic and environmental components of …

Recently, genetic association findings for nicotine dependence, smoking behavior, and
smoking-related diseases converged to implicate the chromosome 15q25. 1 region, which …

Background Chronic obstructive pulmonary disease (COPD) is a complex disease
characterized by impaired lung function and airway obstruction resulting from interactions …