The activated ATM/AMPK/mTOR axis promotes autophagy in response to oxidative stress-mediated DNA damage co-induced by molybdenum and cadmium in duck …

W Pu, X Chu, H Guo, G Huang, T Cui, B Huang… - Environmental …, 2023 - Elsevier
Cadmium (Cd) and excess molybdenum (Mo) have multiple organ toxicity, and testis is one
of their important target organs, but the reproductive toxicity of Mo and Cd combined …

Protective mechanism of selenium on mercuric chloride-induced testis injury in chicken via p38 MAPK/ATF2/iNOS signaling pathway

XW Chen, JH Chu, LX Li, PC Gao, ZY Wang, RF Fan - Theriogenology, 2022 - Elsevier
Mercuric chloride (HgCl 2) is a well-known toxic heavy metal contaminant, which causes
male reproductive function defects. Selenium (Se) has been recognized as an effective …

Malathion-induced testicular toxicity in male rats and the protective effect of vitamins C and E

FG Uzun, S Kalender, D Durak, F Demir… - Food and chemical …, 2009 - Elsevier
Sexually mature male Wistar rats (weighing 300–320g and each group 6 animals) were
given malathion (27mg/kg; 1/50 of the LD50 for an oral dose) and/or vitamin C (200mg/kg)+ …

Mechanisms underlying nickel nanoparticle induced reproductive toxicity and chemo-protective effects of vitamin C in male rats

L Kong, W Hu, C Lu, K Cheng, M Tang - Chemosphere, 2019 - Elsevier
The purpose of this research is to go a step further study on the reproductive toxicities and
the underlying mechanisms induced by nickel nanoparticles (NiNPs), and the possible …

Effects of chelating agents on testicular toxicity in mice caused by acute exposure to nickel

J Xie, T Funakoshi, H Shimada, S Kojima - Toxicology, 1995 - Elsevier
N-Benzyl-D-glucaminedithiocarbamate (BGD), diethyldithiocarbamate (DDTC),
dihydroxyethyldithiocarbamate (DHED), trans-1, 2-cyclohexanediamine N, N, N′, N …

Protective roles of selenium on nitric oxide-mediated apoptosis of immune organs induced by cadmium in chickens

L Liu, J Zhang, Z Zhang, H Yao, G Sun, S Xu - Biological trace element …, 2014 - Springer
Little is known about the influence of subchronic cadmium exposure on apoptosis in the
immune organs of birds and the protective effects on apoptosis by selenium against …

[引用][C] Effect of vitamin C and vitamin E on mercuric chloride-induced reproductive toxicity in male rats

K Muthu, P Krishnamoorthy - Biochem Pharmacol, 2012

Epigenetic modification of H3K4 and oxidative stress are involved in MC‐LR‐induced apoptosis in testicular cells of SD rats

L Yuan, H Liu, X Liu, X Zhang, J Wu… - Environmental …, 2020 - Wiley Online Library
Microcystin‐leucine arginine (MC‐LR) is a cyclic heptapeptide, produced by aquatic
cyanobacteria such as microcystis, with strong reproductive toxicity which poses greater …

Effects of chronic manganese (Mn3O4) exposure on selected reproductive parameters in rats

JW Laskey, GL Rehnberg, JF Hein… - Journal of Toxicology …, 1982 - Taylor & Francis
Long‐Evans rats were chronically exposed to dietary Mn 3 O 4 beginning on d 1 of gestation
and continuing through 224 d of age. Dietary concentrations of Mn, as Mn 3 O 4, were 350 …

Spermatogenesis dysfunction induced by PM2. 5 from automobile exhaust via the ROS-mediated MAPK signaling pathway

B Liu, SD Wu, LJ Shen, TX Zhao, Y Wei… - Ecotoxicology and …, 2019 - Elsevier
Long-term exposure to particulate matter 2.5 (PM 2.5) from automobile exhaust impairs
spermatogenesis through oxidative stress injury, but the underlying mechanism is unknown …